Connexin43 hemichannel block protects against retinal pigment epithelial cell barrier breakdown

被引:0
|
作者
Charisse Kuo
Colin R. Green
Ilva D. Rupenthal
Odunayo O. Mugisho
机构
[1] University of Auckland,Buchanan Ocular Therapeutics Unit, Department of Ophthalmology, New Zealand National Eye Centre
[2] University of Auckland,Department of Ophthalmology, New Zealand National Eye Centre
来源
Acta Diabetologica | 2020年 / 57卷
关键词
Connexin43 hemichannels; Diabetic retinopathy; Tight junctions;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:13 / 22
页数:9
相关论文
共 50 条
  • [11] Orally Delivered Connexin43 Hemichannel Blocker, Tonabersat, Inhibits Vascular Breakdown and Inflammasome Activation in a Mouse Model of Diabetic Retinopathy
    Mugisho, Odunayo O.
    Aryal, Jyoti
    Shome, Avik
    Lyon, Heather
    Acosta, Monica L.
    Green, Colin R.
    Rupenthal, Ilva D.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (04)
  • [12] Cell penetrating peptides based on Connexin43 exert neuroprotective effects through the inhibition of glial hemichannel activity
    Talaveron, R.
    Gangoso, E.
    Jaraiz-Rodriguez, M.
    Dominguez-Prieto, M.
    Ezan, P.
    Koulakoff, A.
    Medina, J. M.
    Gaume, C.
    Tabernero, A.
    GLIA, 2017, 65 : E263 - E263
  • [13] Prostones Attenuate the TNFα-Induced Breakdown of the Epithelial Barrier in Retinal Pigment Epithelial Cells
    Cuppoletti, John
    Chakrabarti, Jayati
    Malinowska, Danuta
    Rosenthal, Rita
    Kim, Damon
    Fromm, Anja
    Fromm, Michael
    Roerig, Birgit
    Durai, Malarvizhi
    Ueno, Ryuji
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2013, 54 (15)
  • [14] Ghrelin Protects Heart Against Ischemia-Induced Arrhythmias by Preserving Connexin43 Protein
    Soeki, Takeshi
    Niki, Toshiyuki
    Bando, Sachiko
    Hisaoka, Sahika
    Takeuchi, Hidekazu
    Kusunose, Kenya
    Yamaguchi, Koji
    Hirata, Yoichiro
    Tomita, Noriko
    Taketani, Yoshio
    Iwase, Takashi
    Yamada, Hirotsugu
    Wakatsuki, Tetsuzo
    Akaike, Masashi
    Kangawa, Kenji
    Sata, Masataka
    CIRCULATION, 2010, 122 (21)
  • [15] Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage
    Ramadan, Raghda
    Vromans, Els
    Anang, Dornatien Chuo
    Goetschalckx, Ines
    Hoorelbeke, Delphine
    Decrock, Elke
    Baatout, Sarah
    Leybaert, Luc
    Aerts, An
    FRONTIERS IN PHARMACOLOGY, 2020, 11
  • [16] Connexin 43 contributes to differentiation of retinal pigment epithelial cells via cyclic AMP signaling
    Kojima, Ariko
    Nakahama, Ken-ichi
    Ohno-Matsui, Kyoko
    Shimada, Noriaki
    Mori, Keisuke
    Iseki, Sachiko
    Sato, Tetsuji
    Mochizuki, Manabu
    Morita, Ikuo
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 366 (02) : 532 - 538
  • [17] Connexin43 mimetic peptide reduces vascular leak and retinal ganglion cell death following retinal ischaemia
    Danesh-Meyer, Helen V.
    Kerr, Nathan M.
    Zhang, Jie
    Eady, Elizabeth K.
    O'Carroll, Simon J.
    Nicholson, Louise F. B.
    Johnson, Cameron S.
    Green, Colin R.
    BRAIN, 2012, 135 : 506 - 520
  • [18] Retinal pigment epithelial damage, breakdown of the blood-retinal barrier, and retinal inflammation in dogs with primary glaucoma
    Mangan, Brendan G.
    Al-Yahya, Khaleel
    Chen, Chu-Te
    Gionfriddo, Juliet R.
    Powell, Cynthia C.
    Dubielzig, Richard R.
    Ehrhart, Eugene J.
    Madl, James E.
    VETERINARY OPHTHALMOLOGY, 2007, 10 : 117 - 124
  • [19] Connexin 43 (Cx43) Upregulation Protects Retinal Endothelial Cells Against High Glucose Insult
    Barrette, Kevin
    Challyandra, Lucky
    Roy, Sayon
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2013, 54 (15)
  • [20] Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease
    Gareth W. Price
    Christos E. Chadjichristos
    Panagiotis Kavvadas
    Sydney C. W. Tang
    Wai Han Yiu
    Colin R. Green
    Joe A. Potter
    Eleftherios Siamantouras
    Paul E. Squires
    Claire E. Hills
    Cell Communication and Signaling, 18