A question of library design

被引：0
|
作者：
Philip J. Hajduk
Warren R. J. D. Galloway
David R. Spring
机构：
[1] Abbott Laboratories,Philip J. Hajduk is in the Department of Lead Discovery
[2] Abbott Park,Warren R. J. D. Galloway and David R. Spring are in the Department of Chemistry
[3] Illinois 60064,undefined
[4] USA. philip.hajduk@abbott.com,undefined
[5] University of Cambridge,undefined
[6] Cambridge CB2 1EW,undefined
[7] UK. spring@ch.cam.ac.uk,undefined
来源：
Nature | 2011年 / 470卷
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D O I：
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学科分类号：
摘要：
Two approaches have emerged for creating libraries of compounds for use in biological screening assays for drug discovery — fragment-based ligand design and diversity-oriented synthesis. Advocates of each approach discuss their favoured strategy.
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页码：42 / 43
页数：1
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