Novel mechanistic links between high-protein diets and atherosclerosis

被引：0
|
作者：
Hanrui Zhang
Muredach P. Reilly
机构：
[1] Columbia University Irving Medical Center,Cardiometabolic Genomics Program, Division of Cardiology, Department of Medicine
[2] Columbia University,Irving Institute for Clinical and Translational Research
来源：
Nature Metabolism | 2020年 / 2卷
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摘要：
New research in this issue of Nature Metabolism shows how a high-protein diet increases amino acids in blood and atherosclerotic plaques, and in plaque macrophages activates mTOR signalling, suppresses mitophagy and increases apoptosis, thereby exacerbating atherosclerotic-plaque build-up in genetically modified mouse models.
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页码：7 / 8
页数：1
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