Phase 1 study of MLN8054, a selective inhibitor of Aurora A kinase in patients with advanced solid tumors

被引:0
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作者
E. Claire Dees
Jeffrey R. Infante
Roger B. Cohen
Bert H. O’Neil
Suzanne Jones
Margaret von Mehren
Hadi Danaee
Yih Lee
Jeffrey Ecsedy
Mark Manfredi
Katherine Galvin
Bradley Stringer
Hua Liu
Omar Eton
Howard Fingert
Howard Burris
机构
[1] University of North Carolina,UNC Lineberger Comprehensive Cancer Center
[2] Sarah Cannon Research Institute,undefined
[3] Fox Chase Cancer Center,undefined
[4] Millennium Pharmaceuticals,undefined
[5] Inc.,undefined
[6] Forest Research Institute,undefined
[7] Inc.,undefined
[8] Boston University School of Medicine,undefined
来源
关键词
MLN8054; Aurora A kinase; Dose-limiting toxicity; Pharmacokinetics; Pharmacodynamics;
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页码:945 / 954
页数:9
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