Reaction of 5-hydroxy-3,3,5-trimethylisoxazolidine with acrylic acid esters

被引：0
|
作者：
Ershov A.Yu. [2 ]
Koshmina N.V. [1 ]
Dobrodumov A.V. [1 ]
机构：
[1] Institute of High-Molecular Compounds, Russian Academy of Sciences
[2] St. Petersburg State University
来源：
Chemistry of Heterocyclic Compounds | 1999年 / 35卷 / 7期
关键词：
Spectroscopy; Methyl; Ester; Ethyl; Organic Chemistry;
D O I：
10.1007/BF02252110
中图分类号：
学科分类号：
摘要：
The reaction of 5-hydroxy-3,3,5-trimethylisoxazolidine with methyl, ethyl, and tert-butyl acrylates, proceeds as Michael addition, and produces previously unknown 5-hydroxy-3,3,5-trimethylisoxazolidine-2-propionic acid esters. The structures of the obtained products are proved by 1 and 13 NMR spectroscopy and by their subsequent transformation into 5-hydroxy-3,3,5-trimethylisoxazolidine-2-propionic acid. ©1999 KluwerAcademic/Plenum Publishers.
引用
收藏
页码：829 / 831
页数：2
相关论文
共 50 条
  • [41] ORGANOSILICON COMPOUNDS .12. DIETHYLSILANE REACTION WITH COMPLEX ALPHA HYDROXY-ACID ESTERS
    LAPKIN, II
    SUBOCHEV.TY
    POVARNIT.TN
    ZHURNAL OBSHCHEI KHIMII, 1971, 41 (06): : 1263 - &
  • [42] Synthesis of α-hydroxy esters by glyoxylate-ene reaction in Lewis acid chloroaluminate ionic liquids
    Shen, ZL
    He, XJ
    Mo, WM
    Xie, Y
    Hu, BX
    Sun, N
    CHINESE JOURNAL OF CATALYSIS, 2006, 27 (03) : 197 - 199
  • [43] Synthesis of Aryl- and Alkyl-Containing 3-Methylene-5-hydroxy Esters via a Barbier Allylation Reaction
    Bartholomaeus, Albert T. H.
    Roman, David
    Al-Jammal, Walid K.
    Vilotijevic, Ivan
    Beemelmanns, Christine
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2023, 26 (18)
  • [44] Antitumor activity of 5-hydroxy-3′,4′,6,7-tetramethoxyflavone in glioblastoma cell lines and its antagonism with radiotherapy
    Papapetrou, Panagiota
    Dimitriadis, Kyriakos
    Galani, Vasiliki
    Zoi, Vasiliki
    Giannakopoulou, Maria
    Papathanasopoulou, Vasiliki A.
    Sioka, Chrissa
    Tsekeris, Pericles
    Kyritsis, Athanassios P.
    Lazari, Diamanto
    Alexiou, George A.
    BIOMOLECULAR CONCEPTS, 2024, 15 (01)
  • [45] STRUCTURE OF "ALPHA-NITRO-BETA-(INDOLYL-3)ACRYLIC ACID ESTERS
    ABOSKALOVA, NI
    BABIEVSK.KK
    BELIKOV, VM
    PEREKALI.VV
    POLYANSK.AS
    ZHURNAL ORGANICHESKOI KHIMII, 1973, 9 (05): : 1058 - 1063
  • [46] SYNTHESIS AND REACTIONS OF NOVEL SUBSTITUTED 3-HYDROXY-5-IMINOALKANOIC ESTERS
    ALCAIDE, B
    ALAJARIN, R
    PLUMET, J
    RODRIGUEZLOPEZ, J
    SYNTHESIS-STUTTGART, 1988, (06): : 440 - 444
  • [47] A NOVEL ACETYLATION OF QUERCETIN 3,3',4',7-TETRAMETHYL ETHER (5-HYDROXY-3,3',4',7-TETRAMETHOXYFLAVONE)
    LOOKER, JH
    ERNEST, FC
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1954, 76 (01) : 294 - 294
  • [48] FORMATION AND CRYSTAL-STRUCTURE OF 5-[HYDROXY(PHENYL)AMINO]-3,3,5-TRIMETHYL-2-PHENYLISOXAZOLIDINE AND N-(3,3,5-TRIMETHYL-2-PHENYLISOXAZOLIDIN-5-YL)PHENYLAMINYL N-OXIDE (BANFIELD AND KENYONS RADICAL)
    FOSTER, R
    IBALL, J
    NASH, R
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1974, (10): : 1210 - 1214
  • [49] Exploring the binding mechanism of 5-hydroxy-3′,4′,7-trimethoxyflavone with bovine serum albumin: Spectroscopic and computational approach
    Sudha, A.
    Srinivasan, P.
    Thamilarasan, V.
    Sengottuvelan, N.
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2016, 157 : 170 - 181
  • [50] ORGANO-ALUMINUM REAGENTS INDUCED ISOMERIZATION OF 5-HYDROXY-3,3,6-TRIMETHYL-5-HEPTENOIC ACID DELTA-LACTONE TO 2,2,5,5-TETRAMETHYL-1,3-CYCLOHEXANEDIONE
    TOMIOKA, H
    OSHIMA, K
    NOZAKI, H
    TETRAHEDRON LETTERS, 1982, 23 (01) : 99 - 100
12345