The ten genes for breast (and ovarian) cancer susceptibility

被引：0
|
作者：
William D. Foulkes
机构：
[1] McGill University,Departments of Medicine, Human Genetics and Oncology
来源：
Nature Reviews Clinical Oncology | 2021年 / 18卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
ATM, BRCA1, BRCA2, CHEK2, PALB2 and TP53 are all established breast cancer susceptibility genes. Over the past 30 years, many other genes have been proposed as candidates. In these two large studies, the candidacy of several questionable genes has been largely resolved, and a final list of ten genes for breast and, importantly, ovarian cancer risk has emerged.
引用
收藏
页码：259 / 260
页数：1
相关论文
共 50 条
  • [41] Breast cancer risks associated with missense variants in breast cancer susceptibility genes
    Dorling, Leila
    Carvalho, Sara
    Allen, Jamie
    Parsons, Michael T.
    Fortuno, Cristina
    Gonzalez-Neira, Anna
    Heijl, Stephan M.
    Adank, Muriel A.
    Ahearn, Thomas U.
    Andrulis, Irene L.
    Auvinen, Paivi
    Becher, Heiko
    Beckmann, Matthias W.
    Behrens, Sabine
    Bermisheva, Marina
    Bogdanova, Natalia V.
    Bojesen, Stig E.
    Bolla, Manjeet K.
    Bremer, Michael
    Briceno, Ignacio
    Camp, Nicola J.
    Campbell, Archie
    Castelao, Jose E.
    Chang-Claude, Jenny
    Chanock, Stephen J.
    Chenevix-Trench, Georgia
    Collee, J. Margriet
    Czene, Kamila
    Dennis, Joe
    Dork, Thilo
    Eriksson, Mikael
    Evans, D. Gareth
    Fasching, Peter A.
    Figueroa, Jonine
    Flyger, Henrik
    Gabrielson, Marike
    Gago-Dominguez, Manuela
    Garcia-Closas, Montserrat
    Giles, Graham G.
    Glendon, Gord
    Guenel, Pascal
    Gundert, Melanie
    Hadjisavvas, Andreas
    Hahnen, Eric
    Hall, Per
    Hamann, Ute
    Harkness, Elaine F.
    Hartman, Mikael
    Hogervorst, Frans B. L.
    Hollestelle, Antoinette
    GENOME MEDICINE, 2022, 14 (01)
  • [42] Breast cancer risks associated with missense variants in breast cancer susceptibility genes
    Leila Dorling
    Sara Carvalho
    Jamie Allen
    Michael T. Parsons
    Cristina Fortuno
    Anna González-Neira
    Stephan M. Heijl
    Muriel A. Adank
    Thomas U. Ahearn
    Irene L. Andrulis
    Päivi Auvinen
    Heiko Becher
    Matthias W. Beckmann
    Sabine Behrens
    Marina Bermisheva
    Natalia V. Bogdanova
    Stig E. Bojesen
    Manjeet K. Bolla
    Michael Bremer
    Ignacio Briceno
    Nicola J. Camp
    Archie Campbell
    Jose E. Castelao
    Jenny Chang-Claude
    Stephen J. Chanock
    Georgia Chenevix-Trench
    J. Margriet Collée
    Kamila Czene
    Joe Dennis
    Thilo Dörk
    Mikael Eriksson
    D. Gareth Evans
    Peter A. Fasching
    Jonine Figueroa
    Henrik Flyger
    Marike Gabrielson
    Manuela Gago-Dominguez
    Montserrat García-Closas
    Graham G. Giles
    Gord Glendon
    Pascal Guénel
    Melanie Gündert
    Andreas Hadjisavvas
    Eric Hahnen
    Per Hall
    Ute Hamann
    Elaine F. Harkness
    Mikael Hartman
    Frans B. L. Hogervorst
    Antoinette Hollestelle
    Genome Medicine, 14
  • [43] Detection of pathogenic variants in breast cancer susceptibility genes in bilateral breast cancer
    Evans, D. Gareth
    Burghel, George J.
    Schlecht, Helene
    Harkness, Elaine F.
    Gandhi, Ashu
    Howell, Sacha J.
    Howell, Anthony
    Forde, Claire
    Lalloo, Fiona
    Newman, William G.
    Smith, Miriam Jane
    Woodward, Emma Roisin
    JOURNAL OF MEDICAL GENETICS, 2023, 60 (10) : 974 - 979
  • [44] Ten degrees of separation: novel genes affecting outcome in ovarian cancer
    Zand, Behrouz
    Ivan, Cristina
    Pecot, Chad V.
    Rupaimoole, Rajesha
    Dalton, Heather J.
    Bottsford-Miller, Justin
    Hu, Wei
    Nick, Alpa M.
    Sood, Anil K.
    CANCER RESEARCH, 2013, 73 (08)
  • [45] Mutation analysis of the BCCIP gene for breast cancer susceptibility in breast/ovarian cancer families
    Bonache, Sandra
    Gutierrez-Enriquez, Sara
    Tenes, Anna
    Masas, Miriam
    Balmana, Judith
    Diez, Orland
    GYNECOLOGIC ONCOLOGY, 2013, 131 (02) : 460 - 463
  • [46] Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis
    J M Cunningham
    R A Vierkant
    T A Sellers
    C Phelan
    D N Rider
    M Liebow
    J Schildkraut
    A Berchuck
    F J Couch
    X Wang
    B L Fridley
    A Gentry-Maharaj
    U Menon
    E Hogdall
    S Kjaer
    A Whittemore
    R DiCioccio
    H Song
    S A Gayther
    S J Ramus
    P D P Pharaoh
    E L Goode
    British Journal of Cancer, 2009, 101 : 1461 - 1468
  • [47] Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis
    Cunningham, J. M.
    Vierkant, R. A.
    Sellers, T. A.
    Phelan, C.
    Rider, D. N.
    Liebow, M.
    Schildkraut, J.
    Berchuck, A.
    Couch, F. J.
    Wang, X.
    Fridley, B. L.
    Gentry-Maharaj, A.
    Menon, U.
    Hogdall, E.
    Kjaer, S.
    Whittemore, A.
    DiCioccio, R.
    Song, H.
    Gayther, S. A.
    Ramus, S. J.
    Pharaoh, P. D. P.
    Goode, E. L.
    BRITISH JOURNAL OF CANCER, 2009, 101 (08) : 1461 - 1468
  • [48] Functional analysis of candidate genes at ovarian cancer susceptibility loci
    Lawrenson, Kate
    Notaridou, Maria
    Wozniak, Eva
    Ramus, Susan J.
    Gayther, Simon A.
    CANCER RESEARCH, 2011, 71
  • [49] Breast cancer susceptibility variants alter risk in familial ovarian cancer
    A. Latif
    H. J. McBurney
    S. A. Roberts
    F. Lalloo
    A. Howell
    D. G. Evans
    W. G. Newman
    Familial Cancer, 2010, 9 : 503 - 506
  • [50] Breast cancer susceptibility variants alter risk in familial ovarian cancer
    Latif, A.
    McBurney, H. J.
    Roberts, S. A.
    Lalloo, F.
    Howell, A.
    Evans, D. G.
    Newman, W. G.
    FAMILIAL CANCER, 2010, 9 (04) : 503 - 506
12345