Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

被引：0
|
作者：
Ilya M. Flyamer
Johanna Gassler
Maxim Imakaev
Hugo B. Brandão
Sergey V. Ulianov
Nezar Abdennur
Sergey V. Razin
Leonid A. Mirny
Kikuë Tachibana-Konwalski
机构：
[1] IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences,Department of Physics
[2] Vienna Biocenter (VBC),undefined
[3] Institute of Gene Biology,undefined
[4] Russian Academy of Sciences,undefined
[5] Faculty of Biology,undefined
[6] Lomonosov Moscow State University,undefined
[7] Institute for Medical Engineering and Science,undefined
[8] Massachusetts Institute of Technology (MIT),undefined
[9] Massachusetts Institute of Technology (MIT),undefined
[10] Harvard Program in Biophysics,undefined
[11] Harvard University,undefined
[12] Computational and Systems Biology Program,undefined
[13] Massachusetts Institute of Technology (MIT),undefined
[14] ,undefined
[15] †Present address: MRC Human Genetics Unit,undefined
[16] Institute of Genetics and Molecular Medicine,undefined
[17] University of Edinburgh,undefined
[18] Edinburgh EH4 2XU,undefined
[19] UK.,undefined
来源：
Nature | 2017年 / 544卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Using a single-nucleus Hi-C protocol, the authors find that spatial organization of chromatin during oocyte-to-zygote transition differs between paternal and maternal nuclei within a single-cell zygote.
引用
收藏
页码：110 / 114
页数：4
相关论文
共 50 条
  • [41] Model-based imputation enables improved resolution for identifying differential chromatin contacts in single-cell Hi-C data
    Shokraneh, Neda
    Andrews, Megan
    Libbrecht, Maxwell
    MACHINE LEARNING IN COMPUTATIONAL BIOLOGY, VOL 240, 2023, 240
  • [42] Reconstructing diploid 3D chromatin structures from single cell Hi-C data with a polymer-based approach
    Rothoerl, Jan
    Brems, Maarten A.
    Stevens, Tim J.
    Virnau, Peter
    FRONTIERS IN BIOINFORMATICS, 2023, 3
  • [43] Capturing cell type-specific chromatin compartment patterns by applying topic modeling to single-cell Hi-C data
    Kim, Hyeon-Jin
    Ioshikhes, Ilya
    Bonora, Giancarlo
    Ramani, Vijay
    Liu, Jie
    Qiu, Ruolan
    Lee, Choli
    Hesson, Jennifer
    Ware, Carol B.
    Shendure, Jay
    Duan, Zhijun
    Noble, William Stafford
    PLOS COMPUTATIONAL BIOLOGY, 2020, 16 (09)
  • [44] High-Resolution Single-Cell Models of Ensemble Chromatin Structures During Drosophila Embryogenesis from Population HI-C
    Sun, Qiu
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 63A - 63A
  • [45] Single-cell Hi-C bridges microscopy and genome-wide sequencing approaches to study 3D chromatin organization
    Ulianov, Sergey V.
    Tachibana-Konwalski, Kikue
    Razin, Sergey V.
    BIOESSAYS, 2017, 39 (10)
  • [46] DeepLoop robustly maps chromatin interactions from sparse allele-resolved or single-cell Hi-C data at kilobase resolution
    Zhang, Shanshan
    Plummer, Dylan
    Lu, Leina
    Cui, Jian
    Xu, Wanying
    Wang, Miao
    Liu, Xiaoxiao
    Prabhakar, Nachiketh
    Shrinet, Jatin
    Srinivasan, Divyaa
    Fraser, Peter
    Li, Yan
    Li, Jing
    Jin, Fulai
    NATURE GENETICS, 2022, 54 (07) : 1013 - +
  • [47] DeepLoop robustly maps chromatin interactions from sparse allele-resolved or single-cell Hi-C data at kilobase resolution
    Shanshan Zhang
    Dylan Plummer
    Leina Lu
    Jian Cui
    Wanying Xu
    Miao Wang
    Xiaoxiao Liu
    Nachiketh Prabhakar
    Jatin Shrinet
    Divyaa Srinivasan
    Peter Fraser
    Yan Li
    Jing Li
    Fulai Jin
    Nature Genetics, 2022, 54 : 1013 - 1025
  • [48] Single-cell diploid Hi-C reveals the role of spatial aggregations in complex rearrangements and KMT2A fusions in leukemia
    Zhihao Xing
    Huirong Mai
    Xiaorong Liu
    Xiaoying Fu
    Xingliang Zhang
    Lichun Xie
    Yunsheng Chen
    Adam Shlien
    Feiqiu Wen
    Genome Biology, 23
  • [49] Single-cell diploid Hi-C reveals the role of spatial aggregations in complex rearrangements and KMT2A fusions in leukemia
    Xing, Zhihao
    Mai, Huirong
    Liu, Xiaorong
    Fu, Xiaoying
    Zhang, Xingliang
    Xie, Lichun
    Chen, Yunsheng
    Shlien, Adam
    Wen, Feiqiu
    GENOME BIOLOGY, 2022, 23 (01)
  • [50] Hi-C profiling in tissues reveals 3D chromatin-regulated breast tumor heterogeneity informing a looping-mediated therapeutic avenue
    Choppavarapu, Lavanya
    Fang, Kun
    Liu, Tianxiang
    Ohihoin, Aigbe G.
    Jin, Victor X.
    CELL REPORTS, 2025, 44 (04):
12345