Oral Chlamydia trachomatis in patients with established periodontitis

被引:10
|
作者
Reed S.G. [1 ]
Lopatin D.E. [2 ]
Foxman B. [1 ]
Burt B.A. [1 ]
机构
[1] Department of Epidemiology, University of Michigan, MI 48109, Ann Arbor
[2] Department of Biologic and Materials Sciences, University of Michigan, MI 48109, Ann Arbor
关键词
Keywords Chlamydia; Chlamydia trachomatis; Fluorescent antibody technique; Periodontal diseases; Periodontitis;
D O I
10.1007/s007840000083
中图分类号
学科分类号
摘要
Periodontitis is considered a consequence of a pathogenic microbial infection at the periodontal site and host susceptibility factors. Periodontal research supports the association of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, and Bacteroides forsythus, and periodontitis; however, causality has not been demonstrated. In pursuit of the etiology of periodontitis, we hypothesized that the intracellular bacteria Chlamydia trachomatis may play a role. As a first step, a cross-sectional study of dental school clinic patients with established periodontitis were assessed for the presence of C. trachomatis in the oral cavity, and in particular from the lining epithelium of periodontal sites. C. trachomatis was detected using a direct fluorescent monoclonal antibody (DFA) in oral specimens from 7% (6/87) of the patients. Four patients tested positive in specimens from the lining epithelium of diseased periodontal sites, one patient tested positive in healthy periodontal sites, and one patient tested positive in the general mucosal specimen. In conclusion, this study provides preliminary evidence of C. trachomatis in the periodontal sites. Planned studies include the use of a more precise periodontal epithelial cell collection device, the newer nucleic acid amplification techniques to detect C. trachomatis, and additional populations to determine the association of C. trachomatis and periodontitis.
引用
收藏
页码:226 / 232
页数:6
相关论文
共 50 条
  • [31] Chlamydia trachomatis testing
    Reust, CE
    ARCHIVES OF FAMILY MEDICINE, 2000, 9 (09) : 885 - 886
  • [32] Spontaneous clearance of Chlamydia trachomatis infection in untreated patients
    Parks, KS
    Dixon, PB
    Richey, CM
    Hook, EW
    SEXUALLY TRANSMITTED DISEASES, 1997, 24 (04) : 229 - 235
  • [33] CHLAMYDIA-TRACHOMATIS INFECTION IN PATIENTS WITH ACUTE SALPINGITIS
    MARDH, PA
    RIPA, T
    SVENSSON, L
    WESTROM, L
    NEW ENGLAND JOURNAL OF MEDICINE, 1977, 296 (24): : 1377 - 1379
  • [34] PREVALENCE OF CHLAMYDIA-TRACHOMATIS INFECTION IN PREGNANT PATIENTS
    MUCH, DH
    YEH, SY
    PUBLIC HEALTH REPORTS, 1991, 106 (05) : 490 - 493
  • [35] AUTOANTIBODIES IN PATIENTS WITH ACUTE SALPINGITIS CAUSED BY CHLAMYDIA TRACHOMATIS
    ANDERSEN, P
    MOLLER, BR
    SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 1982, 14 (01) : 19 - 21
  • [36] Chlamydia trachomatis in andrologic patients -: Direct and indirect detection
    Bollmann, R
    Engel, S
    Petzoldt, R
    Göbel, UB
    INFECTION, 2001, 29 (03) : 113 - 118
  • [37] Chlamydia trachomatis in Andrologic Patients – Direct and Indirect Detection
    R. Bollmann
    S. Engel
    R. Petzoldt
    U.B. Göbel
    Infection, 2001, 29 : 113 - 118
  • [38] Chlamydia trachomatis infections
    Lane, Alison B.
    Decker, Catherine F.
    DM DISEASE-A-MONTH, 2016, 62 (08): : 269 - 273
  • [39] Chlamydia trachomatis proctitis
    Ootani, A
    Mizuguchi, M
    Tsunada, S
    Sakata, H
    Iwakiri, R
    Toda, S
    Fujimoto, K
    GASTROINTESTINAL ENDOSCOPY, 2004, 60 (01) : 161 - 162
  • [40] MAb to Chlamydia trachomatis
    Mittal, Aruna
    HYBRIDOMA, 2006, 25 (05): : 314 - 315