Clinical efficacy and safety of dotinurad, a novel selective urate reabsorption inhibitor, in Japanese hyperuricemic patients with or without gout: an exploratory, randomized, multicenter, double-blind, placebo-controlled, parallel-group early phase 2 study

被引：0
|
作者：
Tatsuo Hosoya
Takafumi Sano
Tomomitsu Sasaki
Masahiko Fushimi
Tetsuo Ohashi
机构：
[1] Jikei University School of Medicine,Medical R&D Division, Development Department
[2] Fuji Yakuhin Co.,undefined
[3] Ltd.,undefined
来源：
Clinical and Experimental Nephrology | 2020年 / 24卷
关键词：
Hyperuricemia; Gout; Selective urate reabsorption inhibitor; URAT1 inhibitor; Dotinurad; FYU-981;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：44 / 52
页数：8
相关论文
共 50 条
  • [31] Efficacy and Safety of Dichlorphenamide for the Treatment of Periodic Paralysis: a Phase 3 Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial
    Burge, James
    Sansone, Valeria
    McDermott, Michael
    Smith, Patty
    Herr, Barbara
    Tawil, Alrabi
    Pandya, Shree
    Kissel, John
    Ciafaloni, Emma
    Shieh, Perry
    Ralph, Jeffrey
    Amato, Anthony
    Cannon, Stephen
    Trivedi, Jaya
    Barohn, Richard
    Crum, Brian
    Mitsumoto, Hiroshi
    Pestronk, Alan
    Meola, Giovanni
    Conwit, Robin
    Jasek, Mark
    Hanna, Michael
    Griggs, Robert
    NEUROLOGY, 2016, 86
  • [32] Pharmacokinetics, Safety, and Tolerability of Varenicline in Healthy Adolescent Smokers: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study
    Faessel, Helene
    Ravva, Patanjali
    Williams, Kathryn
    CLINICAL THERAPEUTICS, 2009, 31 (01) : 177 - 189
  • [33] Protocol of a randomized, double-blind, placebo-controlled, parallel-group, multicentre study of the efficacy and safety of nicotinamide in patients with Friedreich ataxia (NICOFA)
    Kathrin Reetz
    Ralf-Dieter Hilgers
    Susanne Isfort
    Marc Dohmen
    Claire Didszun
    Kathrin Fedosov
    Jennifer Kistermann
    Caterina Mariotti
    Alexandra Durr
    Sylvia Boesch
    Thomas Klopstock
    Francisco Javier Rodríguez de Rivera Garrido
    Ludger Schöls
    Thomas Klockgether
    Massimo Pandolfo
    Rudolf Korinthenberg
    Philip Lavin
    Geert Molenberghs
    Vincenzo Libri
    Paola Giunti
    Richard Festenstein
    Jörg B. Schulz
    Neurological Research and Practice, 1
  • [34] Effects of tolvaptan on volume overload in Japanese patients with heart failure: Results of a phase II, multicenter, randomized, double-blind, placebo-controlled, parallel-group study
    Matsuzaki M.
    Hori M.
    Izumi T.
    Asanoi H.
    Tsutamoto T.
    Cardiovascular Drugs and Therapy, 2011, 25 (Suppl 1) : S19 - S31
  • [35] Evaluation of the Efficacy and Safety of Terguride in Patients With Fibromyalgia Syndrome Results of a Twelve-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study
    Distler, Oliver
    Eich, Wolfgang
    Dokoupilova, Eva
    Dvorak, Zdenek
    Fleck, Martin
    Gaubitz, Markus
    Hechler, Manfred
    Jansen, Jan-Peter
    Krause, Andreas
    Bendszus, Martin
    Pache, Lothar
    Reiter, Rudolf
    Mueller-Ladner, Ulf
    ARTHRITIS AND RHEUMATISM, 2010, 62 (01): : 291 - 300
  • [36] Gaboxadol in angelman syndrome: A double-blind, parallel-group, randomized placebo-controlled phase 3 study
    Keary, Christopher
    Bird, Lynne M.
    de Wit, Marie-Claire
    Hatti, Shivkumar
    Heimer, Gali
    Heussler, Helen
    Kolevzon, Alexander
    Mathews, Adera
    Ochoa-Lubinoff, Cesar
    Tan, Wen-Hann
    Yan, Ying
    Adams, Maxwell
    EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2023, 47 : 6 - 12
  • [37] A randomized, double-blind, parallel-group, placebo-controlled, multicenter, phase II clinical study of famitinib in the treatment of advanced metastatic colorectal cancer
    Xu, Rui-Hua
    Shen, Lin
    Wang, Keming
    Wu, Gang
    Shi, Chunmei
    Ding, Kefeng
    Lin, Lizhu
    Wang, Jinwan
    Xiong, Jianping
    Wu, Changping
    Li, Jin
    Liu, Yunpeng
    Wang, Dong
    Ba, Yi
    Feng, Jueping
    Bai, Yuxian
    Bi, JingWang
    Ma, Liwen
    Lei, Jian
    Yu, Hao
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (03)
  • [38] Efficacy and safety of rasagiline monotherapy in Japanese patients with early Parkinson's disease: A phase 3, randomized, double-blind, placebo-controlled, multicenter study
    Hattori, N.
    Takeda, A.
    Takeda, S.
    Nishimura, A.
    Kitagawa, T.
    Mochizuki, H.
    Nagai, M.
    Takahashi, R.
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2017, 381 : 231 - 232
  • [39] Phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel-group study of ustekinumab in patients with Takayasu arteritis
    Yoshifuji, Hajime
    Ishii, Tomonori
    Ohashi, Hiroki
    Yoshizawa, Katsunori
    Mihoya, Maki
    Nishikawa, Kazuko
    Nakaoka, Yoshikazu
    RHEUMATOLOGY ADVANCES IN PRACTICE, 2025, 9 (02)
  • [40] Efficacy and safety of teneligliptin added to canagliflozin monotherapy in Japanese patients with type 2 diabetes mellitus: A multicentre, randomized, double-blind, placebo-controlled, parallel-group comparative study
    Kadowaki, Takashi
    Inagaki, Nobuya
    Kondo, Kazuoki
    Nishimura, Kenichi
    Kaneko, Genki
    Maruyama, Nobuko
    Nakanishi, Nobuhiro
    Gouda, Maki
    Iijima, Hiroaki
    Watanabe, Yumi
    DIABETES OBESITY & METABOLISM, 2018, 20 (02): : 453 - 457
12345