Nanostructured magnetic systems have many applications, including potential use in cancer therapy deriving from their ability to heat in alternating magnetic fields. In this work we explore the influence of particle chain formation on the normalized heating properties, or specific loss power (SLP) of both low- (spherical) and high- (parallelepiped) anisotropy ferrite-based magnetic fluids. Analysis of ferromagnetic resonance (FMR) data shows that high particle concentrations correlate with increasing chain length producing decreasing SLP. Monte Carlo simulations corroborate the FMR results. We propose a theoretical model describing dipole interactions valid for the linear response regime to explain the observed trends. This model predicts optimum particle sizes for hyperthermia to about 30% smaller than those previously predicted, depending on the nanoparticle parameters and chain size. Also, optimum chain lengths depended on nanoparticle surface-to-surface distance. Our results might have important implications to cancer treatment and could motivate new strategies to optimize magnetic hyperthermia.
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Wayne State Univ, Dept Phys & Astron, Detroit, MI 48202 USAWayne State Univ, Dept Phys & Astron, Detroit, MI 48202 USA
Palihawadana-Arachchige, Maheshika
Nemala, Humeshkar
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Wayne State Univ, Dept Phys & Astron, Detroit, MI 48202 USA
Univ Nebraska, Dept Biol Syst Engn, Lincoln, NE 68583 USAWayne State Univ, Dept Phys & Astron, Detroit, MI 48202 USA
Nemala, Humeshkar
Naik, Vaman M.
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Univ Michigan, Dept Nat Sci, Dearborn, MI 48128 USAWayne State Univ, Dept Phys & Astron, Detroit, MI 48202 USA
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Natl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, ArgentinaNatl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, Argentina
Coral, Diego F.
Mendoza Zelis, Pedro
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Natl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, ArgentinaNatl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, Argentina
Mendoza Zelis, Pedro
Marciello, Marzia
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CSIC, Mat Sci Inst Madrid ICMM, Dept Biomat & Bioinspired Mat, Sor Juana Ines de la Cruz 3, Madrid 28049, SpainNatl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, Argentina
Marciello, Marzia
del Puerto Morales, Maria
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CSIC, Mat Sci Inst Madrid ICMM, Dept Biomat & Bioinspired Mat, Sor Juana Ines de la Cruz 3, Madrid 28049, SpainNatl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, Argentina
del Puerto Morales, Maria
Craievich, Aldo
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Univ Sao Paulo, Inst Phys, CP 66318, Sao Paulo, SP, BrazilNatl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, Argentina
Craievich, Aldo
Sanchez, Francisco H.
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Natl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, ArgentinaNatl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, Argentina
Sanchez, Francisco H.
Fernandez van Raap, Marcela B.
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Natl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, ArgentinaNatl Univ La Plata, Fac Exact Sci, Dept Phys, Phys Inst La Plata IFLP CONICET, Cc 67, RA-1900 La Plata, Buenos Aires, Argentina