Driving glioblastoma growth by alternative polyadenylation

被引：0
|
作者：
Ting Han
John K Kim
机构：
[1] UT Southwestern Medical Center,Department of Biochemistry
[2] Life Sciences Institute,Department of Human Genetics
[3] University of Michigan,undefined
来源：
Cell Research | 2014年 / 24卷
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学科分类号：
摘要：
Global shortening of 3′ untranslated regions (3′ UTRs) through alternative polyadenylation is an emerging hallmark of cancer. A recent study identifies the cleavage factor Im 25 (CFIm25) as an important mediator of 3′ UTR shortening in glioblastomas and demonstrates a causal relationship between alternative polyadenylation and cancer cell proliferation.
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页码：1023 / 1024
页数：1
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