Protocol of a randomised delayed-start double-blind placebo-controlled multi-centre trial for Levodopa in EArly Parkinson’s disease: the LEAP-study

被引：0
|
作者：
Constant V. M. Verschuur
S. R. Suwijn
B. Post
M. Dijkgraaf
B. R. Bloem
J. J. van Hilten
T. van Laar
G. Tissingh
G. Deuschl
A. E. Lang
R. J. de Haan
R. M. A. de Bie
机构：
[1] University of Amsterdam,Department of Neurology, Academic Medical Center
[2] Radboud University Medical Center,Department of Neurology, Donders Institute for Brain, Cognition and Behavior
[3] Clinical Research Unit,Academic Medical Center
[4] Leiden University Medical Center,Department of Neurology
[5] University Medical Center Groningen,Department of Neurology
[6] Atrium-Orbis Medical Center Heerlen/Sittard,Department of Neurology
[7] University Medical Center Schleswig-Holstein,Department of Neurology
[8] University of Toronto,The Edmond J. Safra Program in Parkinson’s Disease and Morton and Gloria Shulman Movement Disorders Center, Toronto Western Hospital
来源：
BMC Neurology | / 15卷
关键词：
Parkinson’s disease; Levodopa; Randomised delayed-start placebo-controlled trial; Disease modifying;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] OCEAN Study in Parkinson's: Status Update of a Randomised Double-Blind Placebo-Controlled Trial of Opicapone
    Chaudhuri, K.
    Odin, P.
    Ferreira, J.
    Antonini, A.
    Rascol, O.
    Kurtis, M.
    Storch, A.
    Bannister, K.
    Costa, R.
    Magalhaes, D.
    Rocha, J.
    Soares-da-Silva, P.
    EUROPEAN JOURNAL OF NEUROLOGY, 2022, 29 : 619 - 620
  • [22] Pramipexole in patients with early Parkinson's disease (PROUD): a randomised delayed-start trial
    Schapira, Anthony H. V.
    McDermott, Michael P.
    Barone, Paolo
    Comella, Cynthia L.
    Albrecht, Stefan
    Hsu, Helen H.
    Massey, Daniel H.
    Mizuno, Yoshikuni
    Poewe, Werner
    Rascol, Olivier
    Marek, Kenneth
    LANCET NEUROLOGY, 2013, 12 (08): : 747 - 755
  • [23] Methotrexate vs Placebo in Early Tubal Ectopic Pregnancy: A Multi-Centre Double-Blind Randomised Trial
    Casikar, Ishwari
    Lu, Chuan
    Reid, Shannon
    Bignardi, Tommaso
    Mongelli, Max
    Morris, Alastair
    Wild, Richard
    Condous, George
    REVIEWS ON RECENT CLINICAL TRIALS, 2012, 7 (03) : 238 - 243
  • [24] A multi-centre randomised double-blind placebo-controlled trial to evaluate the value of a single bolus intravenous alfentanil in CT colonography
    Boellaard, Thierry N.
    van der Paardt, Marije P.
    Hollmann, Markus W.
    Eberl, Susanne
    Peringa, Jan
    Schouten, Lex J.
    Kavaliauskiene, Giedre
    Runge, Jurgen H.
    Tielbeek, Jeroen A. W.
    Stoker, Jaap
    BMC GASTROENTEROLOGY, 2013, 13
  • [25] A multi-centre randomised double-blind placebo-controlled trial to evaluate the value of a single bolus intravenous alfentanil in CT colonography
    Thierry N Boellaard
    Marije P van der Paardt
    Markus W Hollmann
    Susanne Eberl
    Jan Peringa
    Lex J Schouten
    Giedre Kavaliauskiene
    Jurgen H Runge
    Jeroen AW Tielbeek
    Jaap Stoker
    BMC Gastroenterology, 13
  • [26] DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF LEVODOPA THERAPY IN PARKINSONS DISEASE
    MUENTER, MD
    NEUROLOGY, 1970, 20 (12) : 6 - &
  • [27] Memantine for axial signs in Parkinson's disease: a randomised, double-blind, placebo-controlled pilot study
    Moreau, Caroline
    Delval, Arnaud
    Tiffreau, Vincent
    Defebvre, Luc
    Dujardin, Kathy
    Duhamel, Alain
    Petyt, Gregory
    Hossein-Foucher, Claude
    Blum, David
    Sablonniere, Bernard
    Schraen, Susanna
    Allorge, Delphine
    Destee, Alain
    Bordet, Regis
    Devos, David
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2013, 84 (05): : 552 - 555
  • [28] The effect of amantadine on levodopa-induced dyskinesias in Parkinson's disease: A double-blind, placebo-controlled study
    Snow, BJ
    Macdonald, L
    Mcauley, D
    Wallis, W
    CLINICAL NEUROPHARMACOLOGY, 2000, 23 (02) : 82 - 85
  • [29] Simvastatin as a neuroprotective treatment for Parkinson's disease (PD STAT): protocol for a double-blind, randomised, placebo-controlled futility study
    Carroll, Camille B.
    Webb, Douglas
    Stevens, Kara Nicola
    Vickery, Jane
    Eyre, Vicky
    Ball, Susan
    Wyse, Richard
    Webber, Mike
    Foggo, Andy
    Zajicek, John
    Whone, Alan
    Creanor, Siobhan
    BMJ OPEN, 2019, 9 (10):
  • [30] Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial
    Barone, Paolo
    Poewe, Werner
    Albrecht, Stefan
    Debieuvre, Catherine
    Massey, Dan
    Rascol, Olivier
    Tolosa, Eduardo
    Weintraub, Daniel
    LANCET NEUROLOGY, 2010, 9 (06): : 573 - 580
12345