Single-cell genomic and transcriptomic landscapes of primary and metastatic colorectal cancer tumors

被引：0
|
作者：
Rui Wang
Jingyun Li
Xin Zhou
Yunuo Mao
Wendong Wang
Shuai Gao
Wei Wang
Yuan Gao
Kexuan Chen
Shuntai Yu
Xinglong Wu
Lu Wen
Hao Ge
Wei Fu
Fuchou Tang
机构：
[1] Third Hospital,Biomedical Pioneering Innovation Center, Department of General Surgery, School of Life Sciences
[2] Peking University,Academy for Advanced Interdisciplinary Studies
[3] Beijing Advanced Innovation Center for Genomics & Key Laboratory of Assisted Reproduction,Peking
[4] Ministry of Education,Tsinghua Center for Life Sciences
[5] Peking University,Beijing International Center for Mathematical Research
[6] Peking University,undefined
[7] Peking University Third Hospital Cancer Center,undefined
[8] College of Animal Science and Technology,undefined
[9] China Agricultural University,undefined
[10] Peking University,undefined
来源：
Genome Medicine | / 14卷
关键词：
Metastatic colorectal cancer; Single-cell transcriptome profiling; Lineage tracing; Genotype-phenotype relationship; Mitochondrial mutations; Patient-derived organoids; PPAR signaling pathway;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Single-cell genomic profile-based analysis of tissue differentiation in colorectal cancer
    Hao Jiang
    Hongquan Zhang
    Xuegong Zhang
    Science China(Life Sciences), 2021, (08) : 1311 - 1325
  • [32] Cancer biology deciphered by single-cell transcriptomic sequencing
    Li, Yanmeng
    Jin, Jianshi
    Bai, Fan
    PROTEIN & CELL, 2022, 13 (03) : 167 - 179
  • [33] Cancer biology deciphered by single-cell transcriptomic sequencing
    Yanmeng Li
    Jianshi Jin
    Fan Bai
    Protein & Cell, 2022, 13 (03) : 167 - 179
  • [34] Single-cell genomic profile-based analysis of tissue differentiation in colorectal cancer
    Hao Jiang
    Hongquan Zhang
    Xuegong Zhang
    Science China Life Sciences, 2021, 64 : 1311 - 1325
  • [35] Single-cell genomic profile-based analysis of tissue differentiation in colorectal cancer
    Jiang, Hao
    Zhang, Hongquan
    Zhang, Xuegong
    SCIENCE CHINA-LIFE SCIENCES, 2021, 64 (08) : 1311 - 1325
  • [36] Dissecting the heterogeneities of the tumor microenvironment between metastatic and nonmetastatic primary colorectal cancer patients by single-cell RNA sequencing
    Wang, Sixue
    Deng, Shuangya
    Jin, Xiaoxin
    Chen, Weidong
    Wang, Xiaobo
    Zhan, Haiyan
    Fang, Xiaoling
    Fu, Jie
    LIFE SCIENCES, 2023, 320
  • [37] Single-cell DNA sequencing identifies a late dissemination model in metastatic colorectal cancer
    Leung, Marco L.
    Casasent, Anna
    Wang, Yong
    Sei, Emi
    Navin, Nicholas
    CANCER RESEARCH, 2016, 76
  • [38] Single-cell transcriptome profiling of primary tumors and paired organoids of pancreatobiliary cancer
    Chen, Kai
    Ma, Yongsu
    Zhong, Xiejian
    Lan, Jianqiang
    Long, Di
    Tian, Xiaodong
    Yang, Yanlian
    Yang, Yinmo
    CANCER LETTERS, 2024, 582
  • [39] Revelation of comprehensive cell profiling of primary and metastatic tumour ecosystems in oral squamous cell carcinoma by single-cell transcriptomic analysis
    Liao, Yin-han
    Chen, Li
    Feng, Bing-hua
    Lv, Wei
    Huang, Xuan-ping
    Li, Hao
    Li, Cui-ping
    INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2024, 21 (12): : 2293 - 2304
  • [40] Single-cell and spatial transcriptomic analysis reveals tumor cell heterogeneity and underlying molecular program in colorectal cancer
    Wang, Teng
    Chen, Zhaoming
    Wang, Wang
    Wang, Heng
    Li, Shenglong
    FRONTIERS IN IMMUNOLOGY, 2025, 16
12345