Glutaminyl cyclase activity correlates with levels of Aβ peptides and mediators of angiogenesis in cerebrospinal fluid of Alzheimer’s disease patients

被引:0
|
作者
Claire Bridel
Torsten Hoffmann
Antje Meyer
Sisi Durieux
Marleen A. Koel-Simmelink
Matthias Orth
Philip Scheltens
Inge Lues
Charlotte E. Teunissen
机构
[1] VU University Medical Centre Amsterdam,Neurochemistry Lab and Biobank, Department of Clinical Chemistry
[2] Probiodrug AG,Department of Neurology, Alzheimer Center
[3] Swiss BioQuant AG,undefined
[4] VU University Medical Centre Amsterdam,undefined
来源
Alzheimer's Research & Therapy | / 9卷
关键词
Alzheimer’s disease; Cerebrospinal fluid; Glutaminyl cyclase; Amyloid beta; 3pE-Aβ42;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] The Development of Small Molecule Inhibitors of Glutaminyl Cyclase and Isoglutaminyl Cyclase for Alzheimer's Disease
    Xu, Ana
    He, Feng
    Yu, Chenggong
    Qu, Ying
    Zhang, Qiuqiong
    Lv, Jiahui
    Zhang, Xiangna
    Ran, Yingying
    Wei, Chao
    Wu, Jingde
    CHEMISTRYSELECT, 2019, 4 (35): : 10591 - 10600
  • [32] Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease
    Kvartsberg, Hlin
    Duits, Flora H.
    Ingelsson, Martin
    Andreasen, Niels
    Ohrfelt, Annika
    Andersson, Kerstin
    Brinkmalm, Gunnar
    Lannfelt, Lars
    Minthon, Lennart
    Hansson, Oskar
    Andreasson, Ulf
    Teunissen, Charlotte E.
    Scheltens, Philip
    Van der Flier, Wiesje M.
    Zetterberg, Henrik
    Portelius, Erik
    Blennow, Kaj
    ALZHEIMERS & DEMENTIA, 2015, 11 (10) : 1180 - 1190
  • [33] Cerebrospinal fluid production in Alzheimer's disease patients
    Religa, D.
    Andreasen, N.
    EUROPEAN JOURNAL OF NEUROLOGY, 2007, 14 : 318 - 318
  • [34] Aminoterminally Truncated and Oxidized Amyloid-β Peptides in the Cerebrospinal Fluid of Alzheimer's Disease Patients
    Bibl, Mirko
    Gallus, Marion
    Welge, Volker
    Esselmann, Hermann
    Wiltfang, Jens
    JOURNAL OF ALZHEIMERS DISEASE, 2012, 29 (04) : 809 - 816
  • [35] INHIBITION OF GLUTAMINYL CYCLASE TARGETING NEURODEGENERATION AND NEUROINFLAMMATION IN ALZHEIMER'S DISEASE
    Demuth, Hans-Ulrich
    Schilling, S.
    Cynis, H.
    Heiser, U.
    Manhart, S.
    Graubner, S.
    Alexandru, A.
    Jagla, W.
    Lues, I.
    Weber, F.
    Glund, K.
    NEUROBIOLOGY OF AGING, 2012, 33 : S7 - S7
  • [36] CEREBROSPINAL FLUID CORRELATES OF NEUROPSYCHIATRIC SYMPTOMS IN PATIENTS WITH ALZHEIMER'S DISEASE/MILD COGNITIVE IMPAIRMENT
    Showraki, Alireza
    Murari, Geetanjali
    Ismail, Zahinoor
    Barfett, Joseph
    Munoz, David
    Schweizer, Tom
    Fornazzari, Luis
    Fischer, Corinne
    AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2019, 27 (03): : S88 - S89
  • [37] Total glutamine synthetase levels in cerebrospinal fluid of Alzheimer's disease patients are unchanged
    Timmer, Nienke M.
    Herbert, Megan K.
    Claassen, Jurgen A. H. R.
    Kuiperij, H. Bea
    Verbeek, Marcel M.
    NEUROBIOLOGY OF AGING, 2015, 36 (03) : 1271 - 1273
  • [38] Apolipoprotein E Levels in the Cerebrospinal Fluid of North Indian Patients With Alzheimer's Disease
    Kandimalla, Ramesh J. L.
    Wani, Willayat Yousuf
    Anand, R.
    Kaushal, Alka
    Prabhakar, Sudesh
    Grover, Vinod K.
    Bharadwaj, Neerja
    Jain, Kajal
    Gill, Kiran Dip
    AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS, 2013, 28 (03): : 258 - 262
  • [39] Levels of cerebrospinal fluid apolipoprotein E in patients with Alzheimer's disease and healthy controls
    Hahne, S
    Nordstedt, C
    Ahlin, A
    Nyback, H
    NEUROSCIENCE LETTERS, 1997, 224 (02) : 99 - 102
  • [40] The level of cerebrospinal fluid tau correlates with neurofibrillary tangles in Alzheimer's disease
    Tapiola, T
    Overmyer, M
    Lehtovirta, M
    Helisalmi, S
    Ramberg, J
    Alafuzoff, I
    Riekkinen, P
    Soininen, H
    NEUROREPORT, 1997, 8 (18) : 3961 - 3963