Magnesium Sulfate Evokes Endothelium-Independent Relaxation in the Chicken Ductus Arteriosus

被引：0
|
作者：
Y Dias-Guichot
E Verver
S Van Der Sterren
E Villamor
机构：
[1] Pediatrics,
[2] Maastricht University Medical Center (MUMC+),undefined
[3] GROW School,undefined
来源：
Pediatric Research | 2011年 / 70卷
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摘要：
Background and aims: Magnesium sulfate (MgSO4) is widely used as tocolytic agent and for the prophylaxis of seizures in pre-eclampsia. Antenatal exposure to MgSO4 has been associated with a higher risk of patent DA in preterm infants. MgSO4 is a vasodilator and thus may exert a direct relaxant effect in the DA. Here we aimed to investigate the possible vasoactive effects of MgSO4 in the chicken DA.
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页码：285 / 285
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