Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals

被引：0
|
作者：
Wenjuan Dai
Yilin Wang
Tianxiao Yang
Jing Wang
Weicheng Wu
Jianxin Gu
机构：
[1] School of Basic Medical Sciences,Key Laboratory of Glycoconjugate Research Ministry of Health; Department of Biochemistry and Molecular Biology
[2] Fudan University,The Key Laboratory of Public Health and Safety of Education Ministry
[3] School of Public Health; School of Life Sciences and Human Phenome Institute,Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Key Laboratory for Endocrine Tumors
[4] Fudan University,undefined
[5] Department of Hepatic Surgery,undefined
[6] Fudan University Shanghai Cancer Center; Department of Oncology,undefined
[7] Shanghai Medical College,undefined
[8] Fudan University,undefined
[9] Rui-Jin Hospital,undefined
[10] Shanghai Jiao-Tong University School of Medicine,undefined
来源：
Cell Communication and Signaling | / 17卷
关键词：
CLEC3B; Exosomes; Hepatocellular carcinoma; Endothelial cells; VEGF; AMPK;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] CLEC3B Inhibits Invasion and Metastasis of Esophageal Squamous Cell Carcinoma by Regulating Cellular Inflammation, DNA Damage and Cell Cycle
    Mo, Lin
    Wang, Xiao-Lin
    Gao, Jian
    Zhao, Qi
    Jian, Shun-Hai
    JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 2023, 37 (12): : 6643 - 6655
  • [22] Erratum: Argonaute 2 promotes angiogenesis via the PTEN/VEGF signaling pathway in human hepatocellular carcinoma
    Acta Pharmacologica Sinica, 2018, 39 : 329 - 329
  • [23] Exosomal microRNA-23b-3p promotes tumor angiogenesis and metastasis by targeting PTEN in salivary adenoid cystic carcinoma
    Hou, Chen-Xing
    Sun, Nan-Nan
    Han, Wei
    Meng, Ying
    Wang, Chen-Xing
    Zhu, Qing-Hai
    Tang, Yu-Ting
    Ye, Jin-Hai
    CARCINOGENESIS, 2022, 43 (07) : 682 - 692
  • [24] FNDC3B promotes cell migration and tumor metastasis in hepatocellular carcinoma
    Lin, Chin-Hui
    Lin, Yao-Wen
    Chen, Ying-Chun
    Liao, Chen-Chung
    Jou, Yuh-Shan
    Hsu, Ming-Ta
    Chen, Chian-Feng
    ONCOTARGET, 2016, 7 (31) : 49498 - 49508
  • [25] Exosomal delivery of miR-200b-3p suppresses the growth of hepatocellular carcinoma cells by targeting ERG- and VEGF-mediated angiogenesis
    Wang, Yuze
    Moh-Moh-Aung, Aye
    Wang, Tianyi
    Fujisawa, Masayoshi
    Ohara, Toshiaki
    Yamamoto, Ken-ichi
    Sakaguchi, Masakiyo
    Yoshimura, Teizo
    Matsukawa, Akihiro
    GENE, 2024, 931
  • [26] Lenalidomide induces apoptosis and inhibits angiogenesis via caspase-3 and VEGF in hepatocellular carcinoma cells
    Qu, Zhen
    Jiang, Chunping
    Wu, Junhua
    Ding, Yitao
    MOLECULAR MEDICINE REPORTS, 2016, 14 (05) : 4781 - 4786
  • [27] ERO1α promotes hepatocellular carcinoma metastasis and angiogenesis through S1PR1/STAT3/VEGF-A pathway
    Rao, J.
    Yang, S.
    Yang, C.
    Hu, Y.
    Wang, X.
    Lu, L.
    TRANSPLANTATION, 2018, 102 : 311 - 311
  • [28] FGFR3 promotes angiogenesis-dependent metastasis of hepatocellular carcinoma via facilitating MCP-1-mediated vascular formation
    Liu, Xinyu
    Jing, Xiaoqian
    Cheng, Xi
    Ma, Ding
    Jin, Zhijian
    Yang, Weiping
    Qiu, Weihua
    MEDICAL ONCOLOGY, 2016, 33 (05)
  • [29] FGFR3 promotes angiogenesis-dependent metastasis of hepatocellular carcinoma via facilitating MCP-1-mediated vascular formation
    Xinyu Liu
    Xiaoqian Jing
    Xi Cheng
    Ding Ma
    Zhijian Jin
    Weiping Yang
    Weihua Qiu
    Medical Oncology, 2016, 33
  • [30] CXCL17 promotes cell metastasis and inhibits autophagy via the LKB1-AMPK pathway in hepatocellular carcinoma
    Wang, Linpei
    Li, Haitao
    Zhen, Zuojun
    Ma, Xiaoqiu
    Yu, Waishi
    Zeng, Huahuo
    Li, Li
    GENE, 2019, 690 : 129 - 136
12345