Permeability of Articular Cartilage to Matrix Metalloprotease Inhibitors

被引:0
|
作者
Sean X. Peng
Edward C. VonBargen
David M. Bornes
Stanislaw Pikul
机构
[1] The Procter & Gamble Company,Health Care Research Center
来源
Pharmaceutical Research | 1998年 / 15卷
关键词
cartilage permeability; matrix metal loprotease inhibitors; hydrophilicity; cartilage location; HPLC;
D O I
暂无
中图分类号
学科分类号
摘要
Purpose. To develop an in vitro cartilage permeation model for cartilage permeability study and to evaluate the effects of molecular hydrophilicity and cartilage location on the permeability of articular cartilage to matrix metalloprotease inhibitors.
引用
收藏
页码:1414 / 1418
页数:4
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