Drug-Loaded Chondroitin Sulfate Microspheres Generated from Microfluidic Electrospray for Wound Healing

被引：0
|
作者：
Hongzhen Zhang
Ronghua Xu
Zuowen Yin
Jun Yu
Ning Liang
Qian Geng
机构：
[1] Huazhong University of Science and Technology Union Shenzhen Hospital,Gastrointestinal surgery
[2] The Affiliated Changzhou No.2 People’s Hospital with Nanjing Medical University,Department of Dermatology
[3] Huazhong University of Science and Technology Union Shenzhen Hospital,Emergency department
来源：
Macromolecular Research | 2022年 / 30卷
关键词：
drug-loading; chondroitin sulfate; microspheres; microfluidic electrospray; wound healing;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Wound treatment is an important issue and poses a critical challenge for healthcare systems. It is of great significance to develop materials for wound repair and regeneration. Herein, we presented a kind of novel drug-loaded methacryloyl chondroitin sulfate (CSMA) microspheres for promoting the wound healing process. The CSMA droplets were generated from microfluidic electrospray and polymerized with ultraviolet light. With further freeze-drying and drug uploading, the drug-loaded CSMA microspheres were achieved. The prepared microspheres exhibited excellent biocompatibility, and the following animal experiments indicated they could promote wound healing significantly. This study opens the door to drug-loaded CSMA microspheres for wound healing applications.
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页码：36 / 42
页数：6
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