Synthesis, Transformations, and Physicochemical Properties of 3-(4′-Methylphenyl)-8-Methylxanthine Derivatives

被引：0
|
作者：
E. V. Aleksandrova
S. V. Levich
N. I. Romanenko
A. S. Shkoda
E. K. Mikhal′chenko
机构：
[1] Zaporozhe State Medical University,
来源：
Chemistry of Natural Compounds | 2014年 / 49卷
关键词：
xanthines; synthesis; PMR spectroscopy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A preparative method for producing of 3-(4′-methylphenyl)-8-methylxanthine, its 7-substituted derivatives, 3-(4′-methylphenyl)-8-methylxanthinyl-7-acetic acid, its ester, amide, hydrazide, ylidenehydrazides, and N-phenylhydrazinocarbothiamide was developed. The structure of the cyclization product of the last, 3-(4′-methylphenyl)-7-[2-(4″-phenyl-5″-thio-4″H-[1″,2″,4″]triazol-3″-yl)methyl]xanthine, was confirmed by elemental analysis and PMR spectroscopy.
引用
收藏
页码：1105 / 1109
页数：4
相关论文
共 50 条
  • [21] 3-[(Cyclohexylidene)amino]-1-(4-methylphenyl)thiourea
    Zhang, Yan-Ling
    Zhang, Xiao-Wei
    Zhang, Fu-Juan
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O1268 - U1712
  • [22] [3-(4-methylphenyl)isoxazol-5-yl]methanol
    Tian, Da-Min
    Li, Xiang
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2006, 62 : O5335 - O5336
  • [23] PREPARATION OF ENANTIOMERICALLY PURE BUTENOLIDES - 4-HYDROXYMETHYL BUTYROLACTONE DERIVATIVES FROM (+)-(R)-3-(4-METHYLPHENYL)SULPHINYLPROPIONIC ACID
    BRAVO, P
    RESNATI, G
    VIANI, F
    GAZZETTA CHIMICA ITALIANA, 1987, 117 (12): : 747 - 750
  • [24] Structural and physicochemical properties of 3-(3-carboxyphenylaminomethylene)-2-methoxychroman-4-one
    Dziewulska-Kulaczkowska, Agnieszka
    Bartyzel, Agata
    JOURNAL OF MOLECULAR STRUCTURE, 2013, 1033 : 67 - 74
  • [25] SYNTHESIS AND PHYSICOCHEMICAL PROPERTIES OF 3-(4-ALKYLCYCLOHEXYLAMINO)-1-PROPANESULFONIC ACIDS AND SOME RELATED-COMPOUNDS
    KANETANI, F
    TOKUNAGA, A
    NEGORO, K
    NIPPON KAGAKU KAISHI, 1982, (09) : 1531 - 1537
  • [26] SYNTHESIS OF 3-(PYRIMIDINYL)PYRROLE DERIVATIVES
    Nestorak, Igor Yu.
    Tverdokhlebov, Anton V.
    Tolmachev, Andrey A.
    Volovenko, Yulian M.
    HETEROCYCLES, 2010, 81 (03) : 611 - 623
  • [27] Synthesis and Determination of Physicochemical Properties of New 3-(4-Arylpiperazin-1-yl)-2-hydroxypropyl 4-Alkoxyethoxybenzoates
    Marvanova, Pavlina
    Padrtova, Tereza
    Odehnalova, Klara
    Hosik, Ondrej
    Oravec, Michal
    Mokry, Petr
    MOLECULES, 2016, 21 (12)
  • [28] SYNTHESIS OF 1-(4-METHYLPHENYL)-3-HYDROXY-PYRIDAZIN-6-ONE DERIVATIVES
    BALONIAK, S
    MELZER, E
    ACTA POLONIAE PHARMACEUTICA, 1979, 36 (02): : 147 - 154
  • [29] Synthesis of N’-substituted derivatives of 5-(4-methylphenyl)isoxazole-3-carbohydrazonamide
    V. I. Potkin
    E. A. Dikusar
    S. K. Petkevich
    T. D. Zvereva
    G. G. Levkovskaya
    I. B. Rozentsveig
    Russian Journal of General Chemistry, 2016, 86 : 2059 - 2066
  • [30] Synthesis of N'-substituted derivatives of 5-(4-methylphenyl)isoxazole-3-carbohydrazonamide
    Potkin, V. I.
    Dikusar, E. A.
    Petkevich, S. K.
    Zvereva, T. D.
    Levkovskaya, G. G.
    Rozentsveig, I. B.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2016, 86 (09) : 2059 - 2066
12345