Synthesis, Transformations, and Physicochemical Properties of 3-(4′-Methylphenyl)-8-Methylxanthine Derivatives

被引:0
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作者
E. V. Aleksandrova
S. V. Levich
N. I. Romanenko
A. S. Shkoda
E. K. Mikhal′chenko
机构
[1] Zaporozhe State Medical University,
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关键词
xanthines; synthesis; PMR spectroscopy;
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摘要
A preparative method for producing of 3-(4′-methylphenyl)-8-methylxanthine, its 7-substituted derivatives, 3-(4′-methylphenyl)-8-methylxanthinyl-7-acetic acid, its ester, amide, hydrazide, ylidenehydrazides, and N-phenylhydrazinocarbothiamide was developed. The structure of the cyclization product of the last, 3-(4′-methylphenyl)-7-[2-(4″-phenyl-5″-thio-4″H-[1″,2″,4″]triazol-3″-yl)methyl]xanthine, was confirmed by elemental analysis and PMR spectroscopy.
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页码:1105 / 1109
页数:4
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