Synthesis, physicochemical properties, and protective effects of a novel water-soluble tetrahydrocurcumin-diglutaric acid prodrug on ethanol-induced toxicity in HepG2 cells

被引:0
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作者
Nattapong Jongjitphisut
Rianthong Phumsuay
Worathat Thitikornpong
Paitoon Rashatasakhon
Chawanphat Muangnoi
Opa Vajragupta
Pornchai Rojsitthisak
机构
[1] Chulalongkorn University,Center of Excellence in Natural Products for Ageing and Chronic Diseases
[2] Chulalongkorn University,Pharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences
[3] Mahidol University,Cell and Animal Model Unit, Institute of Nutrition
[4] Chulalongkorn University,Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences
[5] Chulalongkorn University,Department of Chemistry, Faculty of Science
[6] Chulalongkorn University,Molecular Probes for Imaging Research Network, Faculty of Pharmaceutical Sciences
关键词
Tetrahydrocurcumin; Tetrahydrocurcumin-diglutaric acid; Prodrug; Alcoholic liver disease; Oxidative stress;
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学科分类号
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页码:477 / 487
页数:10
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