Synthesis, physicochemical properties, and protective effects of a novel water-soluble tetrahydrocurcumin-diglutaric acid prodrug on ethanol-induced toxicity in HepG2 cells

被引:0
|
作者
Nattapong Jongjitphisut
Rianthong Phumsuay
Worathat Thitikornpong
Paitoon Rashatasakhon
Chawanphat Muangnoi
Opa Vajragupta
Pornchai Rojsitthisak
机构
[1] Chulalongkorn University,Center of Excellence in Natural Products for Ageing and Chronic Diseases
[2] Chulalongkorn University,Pharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences
[3] Mahidol University,Cell and Animal Model Unit, Institute of Nutrition
[4] Chulalongkorn University,Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences
[5] Chulalongkorn University,Department of Chemistry, Faculty of Science
[6] Chulalongkorn University,Molecular Probes for Imaging Research Network, Faculty of Pharmaceutical Sciences
关键词
Tetrahydrocurcumin; Tetrahydrocurcumin-diglutaric acid; Prodrug; Alcoholic liver disease; Oxidative stress;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:477 / 487
页数:10
相关论文
共 50 条
  • [1] Synthesis, physicochemical properties, and protective effects of a novel water-soluble tetrahydrocurcumin-diglutaric acid prodrug on ethanol-induced toxicity in HepG2 cells
    Jongjitphisut, Nattapong
    Phumsuay, Rianthong
    Thitikornpong, Worathat
    Rashatasakhon, Paitoon
    Muangnoi, Chawanphat
    Vajragupta, Opa
    Rojsitthisak, Pornchai
    JOURNAL OF PHARMACEUTICAL INVESTIGATION, 2022, 52 (04) : 477 - 487
  • [2] Protective effects of ellagic acid on ethanol-induced toxicity in hepatic HepG2 cells
    Eun-Hwa Sohn
    Hyun Jung Koo
    Do Thi Thu Hang
    Seon-A Jang
    Seung Namkoong
    Jung Dae Lim
    Se Chan Kang
    Molecular & Cellular Toxicology, 2013, 9 : 249 - 256
  • [3] Protective effects of ellagic acid on ethanol-induced toxicity in hepatic HepG2 cells
    Sohn, Eun-Hwa
    Koo, Hyun Jung
    Do Thi Thu Hang
    Jang, Seon-A
    Namkoong, Seung
    Lim, Jung Dae
    Kang, Se Chan
    MOLECULAR & CELLULAR TOXICOLOGY, 2013, 9 (03) : 249 - 256
  • [4] Protective effects of Ellagic acid on ethanol-induced toxicity in hepatic HepG2 cells
    Kim, Ye-Jin
    Kim, Taeseong
    Namkoog, Seung
    Sohn, Eun-Hwa
    FASEB JOURNAL, 2013, 27
  • [5] Protective effects of betulin and betulinic acid against ethanol-induced cytotoxicity in HepG2 cells
    Szuster-Ciesielska, A
    Kandefer-Szerszen, M
    PHARMACOLOGICAL REPORTS, 2005, 57 (05) : 588 - 595
  • [6] Ivermectin-induced toxicity in HepG2 cells and the protective effect of tetrahydrocurcumin and vitamin C
    Miranda, Camila Araujo
    Mansano, Joao Rodolfo Domingues
    Mingatto, Fabio Erminio
    DRUG AND CHEMICAL TOXICOLOGY, 2024,
  • [7] In vitro antioxidant and protective effects of corn peptides on ethanol-induced damage in HepG2 cells
    She, Xingxing
    Wang, Fei
    Ma, Jun
    Chen, Xi
    Ren, Difeng
    Lu, Jun
    FOOD AND AGRICULTURAL IMMUNOLOGY, 2016, 27 (01) : 99 - 110
  • [8] Effect of green tea and (-)-epigallocatechin gallate on ethanol-induced toxicity in HepG2 cells
    Lee, Sang Il
    Kim, Hyo Jung
    Boo, Yong Chool
    PHYTOTHERAPY RESEARCH, 2008, 22 (05) : 669 - 674
  • [9] Protective Effects of Loquat (Eriobotrya japonica) Leaves against Ethanol-induced Toxicity in HepG2 Cells Transfected with CYP2E1
    Bae, Donghyuck
    You, Yanghee
    Yoon, Ho-Geun
    Kim, Kyungmi
    Lee, Yoo-Hyun
    Kim, Yongjae
    Baek, Humyoung
    Kim, Sunoh
    Lee, Jeongmin
    Jun, Woojin
    FOOD SCIENCE AND BIOTECHNOLOGY, 2010, 19 (04) : 1093 - 1096
  • [10] Protective effects of loquat (Eriobotrya japonica) leaves against ethanol-induced toxicity in HepG2 cells transfected with CYP2E1
    Donghyuck Bae
    Yanghee You
    Ho-Geun Yoon
    Kyungmi Kim
    Yoo-Hyun Lee
    Yongjae Kim
    Humyoung Baek
    Sunoh Kim
    Jeongmin Lee
    Woojin Jun
    Food Science and Biotechnology, 2010, 19 : 1093 - 1096