Somatic PTPN11 mutation with a heterogeneous clonal origin in children with juvenile myelomonocytic leukemia

被引:0
|
作者
H Shimada
T Mori
N Shimasaki
K Shimizu
T Takahashi
K Kosaki
机构
[1] Keio University School of Medicine,Department of Pediatrics
[2] National Cancer Center Research Institute,Molecular Oncology Division
来源
Leukemia | 2004年 / 18卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1142 / 1144
页数:2
相关论文
共 50 条
  • [41] Essential role of PTPN11 mutation in enhanced haematopoietic differentiation potential of induced pluripotent stem cells of juvenile myelomonocytic leukaemia
    Shigemura, Tomonari
    Matsuda, Kazuyuki
    Kurata, Takashi
    Sakashita, Kazuo
    Okuno, Yusuke
    Muramatsu, Hideki
    Yue, Fengming
    Ebihara, Yasuhiro
    Tsuji, Kohichiro
    Sasaki, Katsunori
    Nakahata, Tatsutoshi
    Nakazawa, Yozo
    Koike, Kenichi
    BRITISH JOURNAL OF HAEMATOLOGY, 2019, 187 (02) : 163 - 173
  • [42] Somatic CBL mutation presenting as juvenile myelomonocytic leukemia with vasculitis
    Mishra, Varsha
    Krishnan, V. P.
    Desai, Mukesh
    Manek, Hirva
    Pandrowala, Ambreen
    Bodhanwala, Minnie
    Hiwarkar, Prashant
    PEDIATRIC BLOOD & CANCER, 2023, 70 (06)
  • [43] Myeloid progenitors with PTPN11 and nonRAS pathway gene mutations are refractory to treatment with 6-mercaptopurine in juvenile myelomonocytic leukemia
    Matsuda, K.
    Nakazawa, Y.
    Iwashita, C.
    Kurata, T.
    Hirabayashi, K.
    Saito, S.
    Tanaka, M.
    Yoshikawa, K.
    Yanagisawa, R.
    Sakashita, K.
    Sasaki, S.
    Honda, T.
    Koike, K.
    LEUKEMIA, 2014, 28 (07) : 1545 - 1548
  • [44] Aurora Kinase B/C Inhibitor GSK1070916 Specifically Targets Juvenile Myelomonocytic Leukemia Cells with SHP2(PTPN11) Mutation
    He, Chunxiao
    Zhang, Dengyang
    Guo, Yao
    Zhao, Yuming
    Huang, Junbin
    Xue, Hongman
    Chen, Chun
    Chen, Yun
    Zhao, Zhizhuang Joe
    BLOOD, 2022, 140 : 3092 - 3092
  • [45] Role of lncRNA Morrbid in PTPN11(Shp2)E76K-driven juvenile myelomonocytic leukemia
    Cai, Zhigang
    Zhang, Chi
    Kotzin, Jonathan J.
    Williams, Adam
    Henao-Mejia, Jorge
    Kapur, Reuben
    BLOOD ADVANCES, 2020, 4 (14) : 3246 - 3251
  • [46] Negative Regulation of Stat3 by Activating PTPN11 Mutants Contributes to the Pathogenesis of Noonan Syndrome and Juvenile Myelomonocytic Leukemia
    Zhang, Wenjun
    Chan, Rebecca J.
    Chen, Hanying
    Yang, Zhenyun
    He, Yantao
    Zhang, Xian
    Luo, Yong
    Yin, Fuqing
    Moh, Akira
    Miller, Lucy C.
    Payne, R. Mark
    Zhang, Zhong-Yin
    Fu, Xin-Yuan
    Shou, Weinian
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (33) : 22353 - 22363
  • [47] Myeloid progenitors with PTPN11 and nonRAS pathway gene mutations are refractory to treatment with 6-mercaptopurine in juvenile myelomonocytic leukemia
    K Matsuda
    Y Nakazawa
    C Iwashita
    T Kurata
    K Hirabayashi
    S Saito
    M Tanaka
    K Yoshikawa
    R Yanagisawa
    K Sakashita
    S Sasaki
    T Honda
    K Koike
    Leukemia, 2014, 28 : 1545 - 1548
  • [48] Therapy-related acute myeloid leukemia in a child with Noonan syndrome and clonal duplication of the germline PTPN11 mutation
    Chantrain, Christophe F.
    Jijon, Priscilla
    De Raedt, Thomas
    Vermylen, Christiane
    Poirel, Helene A.
    Legius, Eric
    Brichard, Benedicte
    PEDIATRIC BLOOD & CANCER, 2007, 48 (01) : 101 - 104
  • [49] Azacitidine and Sorafenib Therapy in a Pediatric Patient With Refractory Acute Myeloid Leukemia With Monosomy 7 and Somatic PTPN11 Mutation
    Dahl, Nathan A.
    Michaels, Samantha T.
    McMasters, Richard L.
    Chandra, Sharat
    O'Brien, Maureen M.
    PEDIATRIC BLOOD & CANCER, 2016, 63 (03) : 551 - 553
  • [50] A Patient With LEOPARD Syndrome and PTPN11 Mutation
    Lehmann, Lorenz H.
    Schaeufele, Tim
    Buss, Sebastian J.
    Balanova, Maria
    Hartschuh, Wolfgang
    Ehlermann, Philipp
    Katus, Hugo A.
    CIRCULATION, 2009, 119 (09) : 1328 - 1329