Prognosis of mild cognitive impairment syndrome: Data from a two-year clinical follow-up study

被引：7
|
作者：
Gavrilova S.I. [1 ]
Fedorova Ya.B. [1 ]
Roshchina I.F. [1 ]
Korovaitseva G.I. [1 ]
机构：
[1] Scientific Center for Mental Health, Russian Academy of Medical Sciences, Moscow
来源：
Neuroscience and Behavioral Physiology | 2008年 / 38卷 / 2期
关键词：
Alzheimer's disease; ApoE genotype; Mild cognitive impairment syndrome;
D O I：
10.1007/s11055-008-0018-y
中图分类号：
学科分类号：
摘要：
The psychopathological structure and prognostic significance of mild cognitive impairment syndrome (MCI) were studied in a two-year prospective study of randomized cohorts of elderly subjects whose mental state corresponded to the criteria for MCI. A total of 40 patients aged from 50 to 80 years were studied. Patients underwent clinical history-taking, neuropsychological, psychometric, and genetic investigations (genotyping for ApoE), as well as brain imaging studies. The psychopathological structure and psychometric characteristics of MCI syndrome are presented. Clinical and genetic factors with prognostic significance are identified. © Springer Science+Business Media, Inc. 2008.
引用
收藏
页码：129 / 134
页数：5
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