Characteristics of nanobacteria and their possible role in stone formation

被引：0
|
作者：
E. Olavi Kajander
Neva Ciftcioglu
Katja Aho
Enrique Garcia-Cuerpo
机构：
[1] University of Kuopio,Department of Biochemistry
[2] Kuopio,Nanobac Oy
[3] Houston,USRA
[4] Universidad de Alcala,NASA Johnson Space Center
来源：
Urological Research | 2003年 / 31卷 / 2期
关键词：
Nanobacteria; Calcification; Kidney stones; Nephrolithiasis; Nephrocalcinosis;
D O I：
10.1007/s00240-003-0304-7
中图分类号：
学科分类号：
摘要：
Kidney stone formation is a multifactorial disease in which the defence mechanisms and risk factors are imbalanced in favour of stone formation. We have proposed a novel infectious agent, mineral forming nanobacteria (NB), to be active nidi that attach to, invade and damage the urinary epithelium of collecting ducts and papilla forming the calcium phosphate center(s) found in most kidney stones. Stone formation may proceed in urine supersaturated with calcium phosphate, calcium oxalate and uric acid/urate under the influence of crystallization promoters and inhibitors. Our hypothesis underlines the role of active nidi: even supersaturated urine requires nidi for crystallization to appear.
引用
收藏
页码：47 / 54
页数：7
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