CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-α-induced apoptosis by tumor-associated macrophages

被引:0
|
作者
Ji-Ye Kee
Aya Ito
Shozo Hojo
Isaya Hashimoto
Yoshiko Igarashi
Koichi Tsuneyama
Kazuhiro Tsukada
Tatsuro Irimura
Naotoshi Shibahara
Ichiro Takasaki
Akiko Inujima
Takashi Nakayama
Osamu Yoshie
Hiroaki Sakurai
Ikuo Saiki
Keiichi Koizumi
机构
[1] University of Toyama,Division of Pathogenic Biochemistry
[2] University of Toyama,Division of Kampo Diagnostics, Institute of Natural Medicine
[3] University of Toyama,Department of Surgery (II), Faculty of Medicine
[4] University of Toyama,Department of Pathology (I), Faculty of Medicine
[5] St Luke’s International Medical Center,Institute for Medical Innovation
[6] Kinki University School of Pharmaceutical Sciences,Division of Chemotherapy
[7] Kinki University Faculty of Medicine,Department of Microbiology
[8] University of Toyama,Department of Cancer Cell Biology, Graduate School Medicine and Pharmaceutical Sciences
[9] University of Toyama,Molecular Genetics Research Center
来源
BMC Cancer | / 14卷
关键词
CXCL16; IRF8; TNF-α; Apoptosis; Colorectal liver metastasis;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis
    Palencia-Campos, Adrian
    Ruiz-Canas, Laura
    Abal-Sanisidro, Marcelina
    Lopez-Gil, Juan Carlos
    Batres-Ramos, Sandra
    Saraiva, Sofia Mendes
    Yaguee, Balbino
    Navarro, Diego
    Alcala, Sonia
    Rubiolo, Juan A.
    Bidan, Nadege
    Sanchez, Laura
    Mura, Simona
    Hermann, Patrick C.
    de la Fuente, Maria
    Sainz, Bruno
    JOURNAL OF NANOBIOTECHNOLOGY, 2024, 22 (01)
  • [42] Downregulation of osteoprotegerin in colorectal cancer cells promotes liver metastasis via activating tumor-associated macrophage
    Hirata, Wataru
    Itatani, Yoshiro
    Masui, Hideyuki
    Kawada, Kenji
    Mizuno, Rei
    Yamamoto, Takamasa
    Okamoto, Takuya
    Ogawa, Ryotaro
    Inamoto, Susumu
    Maekawa, Hisatsugu
    Okamura, Ryosuke
    Kiyasu, Yoshiyuki
    Hanada, Keita
    Okamoto, Michio
    Nishikawa, Yasuyo
    Sugimoto, Naoko
    Tamura, Takuya
    Hatano, Etsuro
    Sakai, Yoshiharu
    Obama, Kazutaka
    SCIENTIFIC REPORTS, 2023, 13 (01):
  • [43] Stachydrine targeting tumor-associated macrophages inhibit colorectal cancer liver metastasis by regulating the JAK2/STAT3 pathway
    Gui, Yang
    Xue, Gengchen
    Yuan, Yuyi
    Wang, Jingbo
    Deng, Shuangjiao
    Gao, Fei
    Tian, Yushi
    Zhao, Zhiqiang
    Fan, Heng
    FRONTIERS IN PHARMACOLOGY, 2025, 16
  • [44] Downregulation of osteoprotegerin in colorectal cancer cells promotes liver metastasis via activating tumor-associated macrophage
    Wataru Hirata
    Yoshiro Itatani
    Hideyuki Masui
    Kenji Kawada
    Rei Mizuno
    Takamasa Yamamoto
    Takuya Okamoto
    Ryotaro Ogawa
    Susumu Inamoto
    Hisatsugu Maekawa
    Ryosuke Okamura
    Yoshiyuki Kiyasu
    Keita Hanada
    Michio Okamoto
    Yasuyo Nishikawa
    Naoko Sugimoto
    Takuya Tamura
    Etsuro Hatano
    Yoshiharu Sakai
    Kazutaka Obama
    Scientific Reports, 13 (1)
  • [45] Cancer-promoting tumor-associated macrophages: New vistas and open questions
    Mantovani, Alberto
    Germano, Giovanni
    Marchesi, Federica
    Locatelli, Marco
    Biswas, Subhra K.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2011, 41 (09) : 2522 - 2525
  • [46] Emodin Decreases Tumor-Associated Macrophages Accumulation and Suppresses Bladder Cancer Development by Inhibiting CXCL1 Secretion from Cancer-Associated Fibroblasts
    Yu, Fang
    Yu, Nan
    Zhang, Lei
    Xu, Xiaona
    Zhao, Yan
    Cao, Zipeng
    Wang, Feng
    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2025,
  • [47] Phenotype of tumor-associated macrophages can be used in predictions of metastasis of prostate cancer
    Gaisina, G.
    Danilko, K.
    Kzhyshkowska, J.
    Pavlov, V.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 168 - 168
  • [48] Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis
    Georgoudaki, Anna-Maria
    Prokopec, Kajsa E.
    Boura, Vanessa F.
    Hellqvist, Eva
    Sohn, Silke
    Ostling, Jeanette
    Dahan, Rony
    Harris, Robert A.
    Rantalainen, Mattias
    Klevebring, Daniel
    Sund, Malin
    Brage, Suzanne Egyhazi
    Fuxe, Jonas
    Rolny, Charlotte
    Li, Fubin
    Ravetch, Jeffrey V.
    Karlsson, Mikael C. I.
    CELL REPORTS, 2016, 15 (09): : 2000 - 2011
  • [49] Enrichment of Cancer-Associated Fibroblasts, Macrophages, and Up-Regulated TNF-α Signaling in the Tumor Microenvironment of CMS4 Colorectal Peritoneal Metastasis
    Hoye, Eirik
    Kanduri, Chakravarthi
    Torgunrud, Annette
    Lorenz, Susanne
    Edwin, Bjorn
    Larsen, Stein G.
    Fretland, asmund A.
    Dagenborg, Vegar J.
    Flatmark, Kjersti
    Lund-Andersen, Christin
    CANCER MEDICINE, 2025, 14 (01):
  • [50] Suppression of Colorectal Cancer Liver Metastasis by Apolipoprotein(a) Kringle V in a Nude Mouse Model through the Induction of Apoptosis in Tumor-Associated Endothelial Cells
    Ahn, Jin-Hyung
    Yu, Hyun-Kyung
    Lee, Ho-Jeong
    Hong, Soon Won
    Kim, Sun Jin
    Kim, Jang-Seong
    PLOS ONE, 2014, 9 (04):