Types of nuclear localization signals and mechanisms of protein import into the nucleus

被引：0

作者：

Juane Lu

Tao Wu

Biao Zhang

Suke Liu

Wenjun Song

Jianjun Qiao

Haihua Ruan

机构：

[1] Tianjin University of Commerce,Tianjin Key Laboratory of Food Science and Biotechnology, College of Biotechnology and Food Science

[2] Key Laboratory of Systems Bioengineering,Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology

[3] Ministry of Education,SynBio Research Platform

[4] Tianjin University,undefined

[5] Collaborative Innovation Center of Chemical Science and Engineering,undefined

来源：

Cell Communication and Signaling | / 19卷

关键词：

Nuclear localization signal; Nuclear pore complex; Importin;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Nuclear localization signals (NLS) are generally short peptides that act as a signal fragment that mediates the transport of proteins from the cytoplasm into the nucleus. This NLS-dependent protein recognition, a process necessary for cargo proteins to pass the nuclear envelope through the nuclear pore complex, is facilitated by members of the importin superfamily. Here, we summarized the types of NLS, focused on the recently reported related proteins containing nuclear localization signals, and briefly summarized some mechanisms that do not depend on nuclear localization signals into the nucleus.

引用

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