Microsatellite instability in breast cancer

被引:0
|
作者
Elisa B. Rush
Jacqueline E. Calvano
Kimberly J. Van Zee
Andrew D. Zelenetz
Patrick I. Borgen
机构
[1] Memorial Sloan-Kettering Cancer Center,From the Breast Service, Department of Surgery
[2] Memorial Sloan-Kettering Cancer Center,Lymphoma Service
来源
关键词
Microsatellite; Instability; Breast carcinoma; Mutation;
D O I
暂无
中图分类号
学科分类号
摘要
Background: Microsatellites are short repetitive nucleotide sequences that, through mutation, can undergo either expansion or contraction. This novel mutational mechanism known as microsatellite instability may play a role in carcinogenesis. We investigated the incidence of microsatellite instability in a series of primary breast carcinoma surgical specimens.
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页码:310 / 315
页数:5
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