New N-Mannich bases obtained from isatin and piperazine derivatives: the synthesis and evaluation of antimicrobial activity

被引：0
|
作者：
Andrei V. Bogdanov
Al’bina M. Vazykhova
Nadezhda R. Khasiyatullina
Dmitry B. Krivolapov
Alexey B. Dobrynin
Alexandra D. Voloshina
Vladimir F. Mironov
机构：
[1] Russian Academy of Sciences,A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center
来源：
Chemistry of Heterocyclic Compounds | 2016年 / 52卷
关键词：
isatin; piperazines; aminomethylation; antimicrobial activity; Mannich reaction;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
[graphic not available: see fulltext] A Mannich reaction of isatin with monosubstituted piperazines in the presence of aqueous formaldehyde was used to synthesize new, as well as two previously described derivatives of 1-piperazinomethylisatins, which were further converted to isoindigo derivatives. The antimicrobial activity of the obtained heterocycles was evaluated.
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页码：25 / 30
页数：5
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