The cholinergic anti-inflammatory pathway: towards innovative treatment of rheumatoid arthritis

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作者
Marjolein A. van Maanen
Margriet J. Vervoordeldonk
Paul P. Tak
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[1] Academic Medical Center/University of Amsterdam,
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摘要
Evidence is mounting that the cholinergic pathway is involved in the pathogenesis of rheumatoid arthritis and other immune-mediated inflammatory disorders. This timely article provides an overview of the role of the vagus nerve and α7 nicotinic acetylcholine receptor in this pathway, and highlights novel strategies that could exploit these targets in the treatment of rheumatic diseases.
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页码:229 / 232
页数:3
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