HIV reservoirs: what, where and how to target them

被引:0
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作者
Melissa J. Churchill
Steven G. Deeks
David M. Margolis
Robert F. Siliciano
Ronald Swanstrom
机构
[1] Melissa J. Churchill is at the Centre for Biomedical Research,Steven G. Deeks is at the Department of Medicine
[2] Burnet Institute,and the Department of Medicine
[3] Melbourne,Robert F. Siliciano is at the Department of Medicine and Howard Hughes Medical Institute
[4] Victoria 3004,the Department of Biochemistry and Biophysics
[5] Australia.,undefined
[6] University of California,undefined
[7] San Francisco,undefined
[8] California 94110,undefined
[9] USA.,undefined
[10] David M. Margolis is at the University of North Carolina (UNC) HIV Cure Center,undefined
[11] Institute of Global Health and Infectious Diseases,undefined
[12] University of North Carolina at Chapel Hill,undefined
[13] Chapel Hill,undefined
[14] North Carolina 27599,undefined
[15] USA.,undefined
[16] Johns Hopkins University School of Medicine,undefined
[17] Baltimore,undefined
[18] Maryland 21205,undefined
[19] USA.,undefined
[20] Ronald Swanstrom is at the Lineberger Comprehensive Cancer Center,undefined
[21] and the University of North Carolina (UNC) Center for AIDS Research,undefined
[22] University of North Carolina at Chapel Hill,undefined
[23] Chapel Hill,undefined
[24] North Carolina 27599,undefined
[25] USA.,undefined
来源
Nature Reviews Microbiology | 2016年 / 14卷
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摘要
Viral reservoirs pose a major challenge in the efforts towards curing HIV. Here, Churchill, Deeks, Margolis, Siliciano and Swanstrom discuss the cells and tissues that constitute the viral reservoir, how best to measure it and how to target this source of persistent infection.
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页码:55 / 60
页数:5
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