Real-time acoustic elastic property monitoring of compacts during compaction

被引:0
|
作者
Akseli I. [1 ]
Libordi C. [1 ]
Cetinkaya C. [1 ]
机构
[1] Department of Mechanical and Aeronautical Engineering, Center for Advanced Materials Processing, Clarkson University, Potsdam
基金
美国国家科学基金会;
关键词
Acoustic monitoring techniques; Acoustic ultrasonic measurements; Drug tablet monitoring; Powder compaction; Process analytical technology; Real-time compaction monitoring; Tablet elastic properties;
D O I
10.1007/s12247-008-9029-z
中图分类号
学科分类号
摘要
A nondestructive, real-time acoustic technique for determining elastic properties of compacts during compaction is presented. An acoustic time-of-flight study was conducted, and the extraction of the linear elastic properties of calcium carbonate compacts was demonstrated. To verify the results of the acoustic experiments, a uniaxial compaction investigation was also carried out using a computer-controlled press with an instrumented die. Good agreement between linear elastic properties determined using both acoustic experiments and compaction force-displacement data was observed. This technique has the potential to be used as a real-time compaction monitoring tool. © International Society for Pharmaceutical Engineering 2008.
引用
收藏
页码:134 / 140
页数:6
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