Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis

被引:0
|
作者
Sara Lovisa
Valerie S LeBleu
Björn Tampe
Hikaru Sugimoto
Komal Vadnagara
Julienne L Carstens
Chia-Chin Wu
Yohannes Hagos
Birgitta C Burckhardt
Tsvetelina Pentcheva-Hoang
Hersharan Nischal
James P Allison
Michael Zeisberg
Raghu Kalluri
机构
[1] Metastasis Research Center,Department of Cancer Biology
[2] University of Texas M.D. Anderson Cancer Center,Department of Nephrology and Rheumatology
[3] Göttingen University Medical Center,Department of Genomic Medicine
[4] Georg August University,Department of Immunology
[5] University of Texas M.D. Anderson Cancer Center,undefined
[6] Institute of Systemic Physiology and Pathophysiology,undefined
[7] Göttingen University Medical Center,undefined
[8] Georg August University,undefined
[9] University of Texas M.D. Anderson Cancer Center,undefined
来源
Nature Medicine | 2015年 / 21卷
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学科分类号
摘要
During renal fibrosis epithelial cells undergo a partial epithelial-to-mesenchymal transition that can be targeted to reverse established disease.
引用
收藏
页码:998 / 1009
页数:11
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