Novel glitazones as PPARγ agonists: molecular design, synthesis, glucose uptake activity and 3D QSAR studies

被引:0
|
作者
Subhankar P. Mandal
Aakriti Garg
P. Prabitha
Ashish D. Wadhwani
Laxmi Adhikary
B. R. Prashantha Kumar
机构
[1] JSS Academy of Higher Education and Research,Department of Pharmaceutical Chemistry, JSS College of Pharmacy
[2] JSS College of Pharmacy,Department of Pharmaceutical Biotechnology
[3] Biocon Ltd,Bioanalytical Division
来源
关键词
PPARγ; Pharmacophore; Molecular docking; Glucose uptake assay; 3D-QSAR; CoMSIA;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Molecular docking and 3D-QSAR studies of 4-phenylpiperidine derivatives as μ-opioid agonists
    Liu, Ming
    Hu, Wenxiang
    Liu, Xiaoli
    NATURAL RESOURCES AND SUSTAINABLE DEVELOPMENT, PTS 1-3, 2012, 361-363 : 263 - +
  • [42] Molecular Modeling Study for the Design of Novel Peroxisome Proliferator-Activated Receptor Gamma Agonists Using 3D-QSAR and Molecular Docking
    Jian, Yaning
    He, Yuyu
    Yang, Jingjing
    Han, Wei
    Zhai, Xifeng
    Zhao, Ye
    Li, Yang
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (02)
  • [43] Design, 2D Qsar Studies, Molecular Docking, and Synthesis of Novel Triazole Derivatives intended as an Antifungal Agents
    Yuvarani, K.
    Ramalakshmi, N.
    Arunkumar, S.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2023, 49 (SUPPL 1) : S202 - S223
  • [44] Novel anthraquinone photosensitizers: Synthesis, photoactivity, and 3D-QSAR studies
    Yu, Yongle
    Zhu, Lin
    Shi, Yenong
    Tong, Haowen
    Kowah, Jamal A. H.
    Wang, Lisheng
    Liu, Xu
    JOURNAL OF MOLECULAR STRUCTURE, 2023, 1292
  • [45] Design, 2D Qsar Studies, Molecular Docking, and Synthesis of Novel Triazole Derivatives intended as an Antifungal Agents
    K. Yuvarani
    N. Ramalakshmi
    S. Arunkumar
    Russian Journal of Bioorganic Chemistry, 2023, 49 : S202 - S223
  • [46] Design, synthesis, antifungal activity, and 3D-QSAR of coumarin derivatives
    Wei, Yan
    Peng, Wei
    Wang, Dong
    Hao, Shuang-Hong
    Li, Wen-Wen
    Ding, Fei
    JOURNAL OF PESTICIDE SCIENCE, 2018, 43 (1-2) : 88 - 95
  • [47] Three-dimensional quantitative structure-activity relationships (3D-QSAR) study of PPARγ partial agonists
    Guasch, L.
    Sala, E.
    Pujadas, G.
    Garcia-Vallve, S.
    FEBS JOURNAL, 2010, 277 : 65 - 66
  • [48] Design and Synthesis of Quinazolinone Derivatives as Anti-inflammatory Agents: Pharmacophore Modeling and 3D QSAR Studies
    Chaitanya, P.
    Reddy, G. Deepak
    Varun, G.
    Srikanth, L. M.
    Prasad, V. V. S. R.
    Ravindernath, A.
    MEDICINAL CHEMISTRY, 2014, 10 (07) : 711 - 723
  • [49] 3D QSAR studies on substituted aryl alkanoic acid analogs as GPR40 agonists
    Bhatt, Aaditya
    Patel, Pallav D.
    Patel, Maulik R.
    Singh, Satyakam
    Talele, Tanaji T.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [50] Classical and 3D QSAR studies on inverse agonists of human histamine H1 receptor
    Thangapandian, Sundarapandian
    John, Shalini
    Lee, Keun Woo
    MOLECULAR SIMULATION, 2012, 38 (13) : 1143 - 1156