A new branch connecting thermogenesis and diabetes

被引：0
|
作者：
Haipeng Sun
Yibin Wang
机构：
[1] University of California at Los Angeles,Departments of Anesthesiology, Physiology and Medicine, David Geffen School of Medicine
来源：
Nature Metabolism | 2019年 / 1卷
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D O I：
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学科分类号：
摘要：
Systemic accumulation of branched-chain amino acids (BCAAs) is a major metabolic hallmark and contributor to insulin resistance associated with obesity. A recent report identifies SLC25A44 as the BCAA transporter in mitochondrial membranes and shows that BCAA catabolism in brown adipose tissue significantly affects thermogenic activity, systemic BCAA clearance, energy expenditure and overall metabolic health.
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页码：845 / 846
页数：1
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