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CladribineUse in Therapy of Multiple Sclerosis
被引:0
|作者:
John S. Romine
Jack C. Sipe
James A. Koziol
Jack Zyroff
Robert McMillan
Ernest Beutler
机构:
[1] Scripps Clinic and Research Foundation,Division of Neurology
[2] The Scripps Research Institute,Department of Molecular and Experimental Medicine
[3] Scripps Clinic and Research Foundation,Division of Radiology
来源:
BioDrugs
|
1997年
/
7卷
关键词:
Multiple Sclerosis;
Multiple Sclerosis Patient;
Herpes Zoster;
Expand Disability Status Scale;
Cladribine;
D O I:
暂无
中图分类号:
学科分类号:
摘要:
Cladribine is a novel drug that selectively depletes lymphocytes and may be able to destroy the activated immunocytes that damage the central nervous system in multiple sclerosis. Our initial controlled studies have shown a beneficial, although temporary, dose-related effect of cladribine on the course of chronic progressive multiple sclerosis.
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页码:386 / 393
页数:7
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