Cladribine is a novel drug that selectively depletes lymphocytes and may be able to destroy the activated immunocytes that damage the central nervous system in multiple sclerosis. Our initial controlled studies have shown a beneficial, although temporary, dose-related effect of cladribine on the course of chronic progressive multiple sclerosis.
机构:
Univ Calif San Francisco, Dept Neurol, MS Ctr, San Francisco, CA 94115 USAUniv Calif San Francisco, Dept Neurol, MS Ctr, San Francisco, CA 94115 USA