Investigating receptor-mediated antibody transcytosis using blood–brain barrier organoid arrays

被引:0
|
作者
Claire Simonneau
Martina Duschmalé
Alina Gavrilov
Nathalie Brandenberg
Sylke Hoehnel
Camilla Ceroni
Evodie Lassalle
Elena Kassianidou
Hendrik Knoetgen
Jens Niewoehner
Roberto Villaseñor
机构
[1] Roche Innovation Center Basel,Roche Pharma Research and Early Development (pRED), Pharmaceutical Sciences
[2] SUN bioscience,Roche Pharma Research and Early Development (pRED), Therapeutic Modalities
[3] EPFL Innovation Park,undefined
[4] Roche Innovation Center Munich,undefined
关键词
Blood–brain barrier; Organoids; Receptor-mediated transcytosis; High-throughput in vitro model;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Receptor-Mediated Delivery of Magnetic Nanoparticles across the Blood-Brain Barrier
    Qiao, Ruirui
    Jia, Qiaojuan
    Huewel, Sabine
    Xia, Rui
    Liu, Ting
    Gao, Fabao
    Galla, Hans-Joachim
    Gao, Mingyuan
    ACS NANO, 2012, 6 (04) : 3304 - 3310
  • [32] RECEPTOR-MEDIATED PEPTIDE-TRANSPORT THROUGH THE BLOOD-BRAIN-BARRIER
    PARDRIDGE, WM
    ENDOCRINE REVIEWS, 1986, 7 (03) : 314 - 330
  • [33] RECEPTOR-MEDIATED TRANSPORT OF THERAPEUTICS ACROSS THE BLOOD-BRAIN-BARRIER - COMMENT
    ZLOKOVIC, BV
    NEUROSURGERY, 1994, 35 (02) : 298 - 298
  • [34] Transcytosis at the blood-brain barrier
    Ayloo, Swathi
    Gu, Chenghua
    CURRENT OPINION IN NEUROBIOLOGY, 2019, 57 : 32 - 38
  • [35] Transferrin receptor-mediated transcytosis in intestinal epithelium
    Shen, WC
    Shah, D
    FASEB JOURNAL, 1996, 10 (03): : 699 - 699
  • [36] Transthyretin as a new transporter of nanoparticles for receptor-mediated transcytosis in rat brain microvessels
    Kim, So Yeun
    Choi, Eun-Sook
    Lee, Hyo-Jung
    Moon, Cheil
    Kim, Eunjoo
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2015, 136 : 989 - 996
  • [37] Mouse embryonic stem cell-derived blood-brain barrier model: applicability to studying antibody triggered receptor mediated transcytosis
    Jezierski, Anna
    Huang, Jez
    Haqqani, Arsalan S.
    Haukenfrers, Julie
    Liu, Ziying
    Baumann, Ewa
    Sodja, Caroline
    Charlebois, Claudie
    Delaney, Christie E.
    Star, Alexandra T.
    Liu, Qing
    Stanimirovic, Danica B.
    FLUIDS AND BARRIERS OF THE CNS, 2023, 20 (01)
  • [38] Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood-brain barrier
    Holst, Mikkel Roland
    de Wit, Nienke Marije
    Ozguer, Burak
    Brachner, Andreas
    Hyldig, Kathrine
    Appelt-Menzel, Antje
    Sleven, Hannah
    Cader, Zameel
    de Vries, Helga Eveline
    Neuhaus, Winfried
    Jensen, Allan
    Brodin, Birger
    Nielsen, Morten Schallburg
    FLUIDS AND BARRIERS OF THE CNS, 2023, 20 (01)
  • [39] Standardized Preclinical In Vitro Blood-Brain Barrier Mouse Assay Validates Endocytosis-Dependent Antibody Transcytosis Using Transferrin-Receptor-Mediated Pathways
    Petrovic, Alex
    Metzendorf, Nicole G.
    Rofo, Fadi
    Yilmaz, Canan U.
    Stenler, Sofia
    Laudon, Hanna
    Morrison, Jamie I.
    Hultqvist, Greta
    MOLECULAR PHARMACEUTICS, 2023, : 1564 - 1576
  • [40] Targeting Receptor-Mediated Transport for Delivery of Biologics Across the Blood-Brain Barrier
    Lajoie, Jason M.
    Shusta, Eric V.
    ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 55, 2015, 55 : 613 - 631