Population Pharmacokinetics of Clinafloxacin in Healthy Volunteers and Patients with InfectionsExperience with Heterogeneous Pharmacokinetic Data

被引：0
|
作者：
Bill Frame
Jeffrey Koup
Raymond Miller
Richard Lalonde
机构：
[1] PfizerGlobal Research and Development,Department of Clinical Pharmacokinetics and Pharmacodynamics
来源：
Clinical Pharmacokinetics | 2001年 / 40卷
关键词：
Mixed Effect Modelling; Interindividual Variability; Intraindividual Variability; Clinafloxacin; Combine Phase;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objective: Clinafloxacin is a new fluoroquinolone antibacterial with inhibitory activity against aerobic, anaerobic and atypical bacterial pathogens. The objectives of this study are to evaluate the pharmacokinetics of clinafloxacin in healthy volunteers and patients with infections and to describe our experience with mixed-effects modelling using heterogeneous pharmacokinetic data.
引用
收藏
页码：307 / 315
页数：8
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