Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

被引：0

作者：

Fan Lai

Ulf A. Orom

Matteo Cesaroni

Malte Beringer

Dylan J. Taatjes

Gerd A. Blobel

Ramin Shiekhattar

机构：

[1] The Wistar Institute,Department of Chemistry and Biochemistry

[2] 3601 Spruce Street,Division of Hematology

[3] Max Planck Institute for Molecular Genetics,undefined

[4] Ihnestr,undefined

[5] 14195 Berlin,undefined

[6] Germany,undefined

[7] Center de Regulacio Genomica and UPF,undefined

[8] Barcelona 08003,undefined

[9] Spain,undefined

[10] University of Colorado,undefined

[11] 215 UCB,undefined

[12] Boulder,undefined

[13] Colorado 80309,undefined

[14] USA,undefined

[15] The Children’s Hospital of Philadelphia,undefined

来源：

Nature | 2013年 / 494卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A class of long non-coding RNA (lncRNA) with enhancer-like activity is found to associate with the co-activator complex Mediator and promote its genomic association and enzymatic activity; together with Mediator, the lncRNAs also help to maintain the chromosomal architecture of active regulatory elements.

引用

页码：497 / 501

页数：4

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