Population genetic analysis of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China

被引:0
|
作者
Bo-feng Zhu
Guang Yang
Chun-mei Shen
Hai-xia Qin
Shuan-liang Fan
Li-bin Deng
Feng Chen
Li-ping Chen
Hong-dan Wang
Zhen-yuan Wang
Rudolf Lucas
Zhen-min Lian
机构
[1] Shaanxi Normal University,Mobile post
[2] Shaanxi Normal University,doctoral station
[3] Xi’an Jiaotong University,College of Life Sciences
[4] Medical College of Georgia,Department of Forensic Medicine, School of Medicine
[5] Shaan’xi Blood Center,Vascular Biology Center
[6] Medical College of Georgia,Institute of Molecular Medicine and Genetics
[7] Nanchang University,Faculty of Basic Medical Science
[8] Yanan University,College of Life Sciences
来源
Molecular Biology Reports | 2010年 / 37卷
关键词
Russian population; STR; Population genetics;
D O I
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中图分类号
学科分类号
摘要
In the present study, we investigated the genetic polymorphisms of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China as well as its genetic relationships with other populations. DNA typing for 15 autosomal STR loci was performed on 148 randomly selected healthy individuals from the Russian population living in Eerguna, northeastern Inner-Mongolia. Allelic frequencies of these loci were calculated by direct counting. The genotype data of this Russian population was moreover compared to other populations using neighbor-joining method, as such constructing a phylogenic tree. A total of 143 alleles were found in the Russian population with corresponding allele frequencies in the range from 0.0034 to 0.5372. Among all the 15 loci, D18S51 had the highest polymorphism (PIC = 0.8632), whereas TPOX had the lowest (PIC = 0.5179). In the phylogenic tree, this Russian population has a close relationship with the populations of South Siberia and northeastern Asia. This study may increase our understanding of the genetic background of the Russian population in Eerguna, China as such providing useful information for anthropological research, forensic sciences as well as disease-association studies.
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页码:3889 / 3895
页数:6
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