MicroRNA directly modulates cardiac ion channel

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作者
Ciarán Martin Fitzpatrick
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[1] Editor,
[2] BMC Series,undefined
来源
Nature Reviews Cardiology | 2021年 / 18卷
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摘要
A novel binding mechanism between a microRNA and an inward-rectifier potassium channel has been discovered. MiR-1 directly modulates the function of Kir2.1 to maintain cardiac homeostasis, and disruption to this relationship predisposes the heart to a greater risk of arrhythmogenesis.
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页码:308 / 308
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