LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration

被引:0
|
作者
Jong Min Hong
Jin-Woo Lee
Dong-Seung Seen
Jae-Yeon Jeong
Won-Ki Huh
机构
[1] Seoul National University,School of Biological Sciences
[2] GPCR Therapeutics Inc,Institute of Microbiology
[3] Seoul National University,undefined
关键词
Chemokine receptor 4; Lysophosphatidic acid receptor 1; G protein-coupled receptor; GPCR heteromer; GPCR signaling; Chemotaxis; Cancer; Inflammatory disease;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
    Hong, Jong Min
    Lee, Jin-Woo
    Seen, Dong-Seung
    Jeong, Jae-Yeon
    Huh, Won-Ki
    CELL COMMUNICATION AND SIGNALING, 2023, 21 (01)
  • [2] Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration
    Hayashi, Hisaki
    Kume, Tsutomu
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 367 (03) : 584 - 589
  • [3] The Slit/Robo complex mediates inhibition of CXCR4/CXCL12-induced chemotaxis in T-cells.
    Bailuguttu, A
    Fernandis, AZ
    Ganju, RK
    BLOOD, 2002, 100 (11) : 121A - 121A
  • [4] Deubiquitination of CXCR4 by USP14 Is Critical for Both CXCL12-induced CXCR4 Degradation and Chemotaxis but Not ERK Activation
    Mines, Marjelo A.
    Goodwin, J. Shawn
    Limbird, Lee E.
    Cui, Fei-Fei
    Fan, Guo-Huang
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (09) : 5742 - 5752
  • [5] CXCL12-induced partitioning flotillin-1 with lipid rafts plays a role in CXCR4 function
    Giri, Banabihari
    Dixit, Vishwa D.
    Ghosh, Manik C.
    Collins, Gary D.
    Khan, Islam U.
    Madara, Karen
    Weeraratna, Ashani T.
    Taub, Dennis D.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2007, 37 (08) : 2104 - 2116
  • [6] CXCL12/CXCR4 signalling in neuronal cell migration
    Tiveron, Marie-Catherine
    Cremer, Harold
    CURRENT OPINION IN NEUROBIOLOGY, 2008, 18 (03) : 237 - 244
  • [7] The Role of the CXCL12/CXCR4 Signaling Pathway in Regulating Cellular Migration
    Worden, Austin N.
    Pittard, Emma Grace
    Stern, Matt
    Uline, Mark J.
    Potts, Jay D.
    MICROSCOPY AND MICROANALYSIS, 2025, 31 (02)
  • [8] The role of Hematopoietic Cell Kinase in cell migration and CXCL12/CXCR4 axis
    Roversi, F. M.
    Machado-Neto, J. A.
    Pericole, F. V.
    Longhini, A.
    Duarte, A. D.
    Traina, F.
    Saad, S. T.
    MOLECULAR BIOLOGY OF THE CELL, 2015, 26
  • [9] CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
    Levoye, Angelique
    Balabanian, Karl
    Baleux, Francoise
    Bachelerie, Francoise
    Lagane, Bernard
    BLOOD, 2009, 113 (24) : 6085 - 6093
  • [10] Inhibition of the CXCL12/CXCR4 Pathway in Gammaherpesvirus Induced Lung Fibrosis
    Torres-Gonzalez, E.
    Vanlandingham, S.
    Cardona, A.
    Yoon, Y.
    Rojas, M.
    Neujahr, D.
    Stecenko, A.
    Shim, H.
    Mora, A. L.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 179