The concentration of u-PA and PAI-1 antigen in tissue extracts of nasopharyngeal carcinoma

被引：0
|
作者：
M. Sunagawa
G. W. Huang
M. Nakamura
T. Kosugi
机构：
[1] University of the Ryukyus,1st Department of Physiology, School of Medicine
[2] University of the Ryukyus,1st Department of Physiology and The Research Center of Comprehensive Medicine, School of Medicine
[3] Guangxi Medical University,Department of Otorhinolaryngology
来源：
European Archives of Oto-Rhino-Laryngology | 1997年 / 254卷
关键词：
Nasopharyngeal carcinoma; Urokinasetype plasminogen activator; Plasminogen activator inhibitor-1; Tumor invasion;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We measured the antigen levels of urokinasetype plasminogen activator (u-PA) and plasminogen activator inhibitor-1 (PAI-1) in tissue extracts from nasopharyngeal carcinomas. An increase in u-PA antigen was observed with the advanced stages of disease. However, the levels of PAI-1 antigen decreased with each advanced stage. These results suggest that local administration of antiplasminic agents may be effective in suppressing tumor invasion.
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页码：277 / 280
页数：3
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