Synthesis and properties of 4,5-trans-2-alkylthio-3-cyano-6-hydroxy-6-methyl- 4-phenyl-5-pyridinio-1,4,5,6-tetrahydropyridine iodides

被引：0
|
作者：
Krauze A. [1 ]
Kemme A. [1 ]
Duburs G. [1 ]
机构：
[1] Latvian Institute of Organic Synthesis
来源：
Chemistry of Heterocyclic Compounds | 2001年 / 37卷 / 12期
关键词：
5-pyridiniopyridine iodides; Iodoacetamide; Tetrahydropyridine-2-thiolates; X-ray difraction analysis;
D O I：
10.1023/A:1014565428077
中图分类号：
学科分类号：
摘要：
Alkylation of 4,5-trans-4-aryl-3-cyano-6-hydroxy- 6-methyl-5-pyridinio-1,4,5,6-tetrahydropyridine-2-thiolates 1, 2 was carried out. The presence of 5-pyridinio cation in thiolates 1, 2 as a strong electron- withdrawing group leads to a pronoun- ced enhancement of their stability to dehydration but decreases their reactivity with electrophilic reagents. Steric structures of 2-alkylthio-6-hydroxytetrahydro-pyridines 3-5 are discussed in the light of1H NMR spectra and crystal X-ray diffraction data.
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页码：1541 / 1548
页数：7
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