Synthesis and properties of 4,5-trans-2-alkylthio-3-cyano-6-hydroxy-6-methyl- 4-phenyl-5-pyridinio-1,4,5,6-tetrahydropyridine iodides

被引：0

作者：

Krauze A. ^{[1
]}

Kemme A. ^{[1
]}

Duburs G. ^{[1
]}

机构：

[1] Latvian Institute of Organic Synthesis

来源：

Chemistry of Heterocyclic Compounds | 2001年 / 37卷 / 12期

关键词：

5-pyridiniopyridine iodides; Iodoacetamide; Tetrahydropyridine-2-thiolates; X-ray difraction analysis;

D O I：

10.1023/A:1014565428077

中图分类号：

学科分类号：

摘要：

Alkylation of 4,5-trans-4-aryl-3-cyano-6-hydroxy- 6-methyl-5-pyridinio-1,4,5,6-tetrahydropyridine-2-thiolates 1, 2 was carried out. The presence of 5-pyridinio cation in thiolates 1, 2 as a strong electron- withdrawing group leads to a pronoun- ced enhancement of their stability to dehydration but decreases their reactivity with electrophilic reagents. Steric structures of 2-alkylthio-6-hydroxytetrahydro-pyridines 3-5 are discussed in the light of1H NMR spectra and crystal X-ray diffraction data.

引用

页码：1541 / 1548

页数：7

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