The osteogenic differentiation of human adipose-derived stem cells is regulated through the let-7i-3p/LEF1/β-catenin axis under cyclic strain

被引：0
|
作者：
Yadong Luo
Ran Ge
Heming Wu
Xu Ding
Haiyang Song
Huan Ji
Meng Li
Yunan Ma
Sheng Li
Chenxing Wang
Hongming Du
机构：
[1] Affiliated Stomatological Hospital of Nanjing Medical University,Department of Oral and Maxillofacial Surgery
[2] Nanjing Medical University,Oral Disease Key Laboratory of Jiangsu Province
[3] Fujian Medical University Union Hospital,Department of Nuclear Medicine
来源：
Stem Cell Research & Therapy | / 10卷
关键词：
hASC osteogenic differentiation; Cyclic strain; Wnt/β-catenin pathway; Let-7i-3p; LEF1;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Molecular control of nitric oxide synthesis through eNOS and caveolin-1 interaction regulates osteogenic differentiation of adipose-derived stem cells by modulation of Wnt/β-catenin signaling
    Bandara, Nadeeka
    Gurusinghe, Saliya
    Lim, Shiang Yong
    Chen, Haying
    Chen, Shuangfeng
    Wang, Dawei
    Hilbert, Bryan
    Wang, Le-Xin
    Strappe, Padraig
    STEM CELL RESEARCH & THERAPY, 2016, 7 : 1 - 15
  • [42] Molecular control of nitric oxide synthesis through eNOS and caveolin-1 interaction regulates osteogenic differentiation of adipose-derived stem cells by modulation of Wnt/β-catenin signaling
    Nadeeka Bandara
    Saliya Gurusinghe
    Shiang Yong Lim
    Haying Chen
    Shuangfeng Chen
    Dawei Wang
    Bryan Hilbert
    Le-Xin Wang
    Padraig Strappe
    Stem Cell Research & Therapy, 7
  • [43] RSPO3-LGR4 Regulates Osteogenic Differentiation Of Human Adipose-Derived Stem Cells Via ERK/FGF Signalling
    Min Zhang
    Ping Zhang
    Yunsong Liu
    Longwei Lv
    Xiao Zhang
    Hao Liu
    Yongsheng Zhou
    Scientific Reports, 7
  • [44] RSPO3-LGR4 Regulates Osteogenic Differentiation Of Human Adipose-Derived Stem Cells Via ERK/FGF Signalling
    Zhang, Min
    Zhang, Ping
    Liu, Yunsong
    Lv, Longwei
    Zhang, Xiao
    Liu, Hao
    Zhou, Yongsheng
    SCIENTIFIC REPORTS, 2017, 7
  • [45] The epigenetic promotion of osteogenic differentiation of human adipose-derived stem cells by the genetic and chemical blockade of histone demethylase LSD1
    Ge, Wenshu
    Liu, Yunsong
    Chen, Tong
    Zhang, Xiao
    Lv, Longwei
    Jin, Chanyuan
    Jiang, Yong
    Shi, Lei
    Zhou, Yongsheng
    BIOMATERIALS, 2014, 35 (23) : 6015 - 6025
  • [46] Knockdown of ARL4C inhibits osteogenic differentiation of human adipose-derived stem cells through disruption of the Wnt signaling pathway
    Wang, Wensi
    Wang, Siyi
    Liu, Xuenan
    Gu, Ranli
    Zhu, Yuan
    Zhang, Ping
    Liu, Yunsong
    Zhou, Yongsheng
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 497 (01) : 256 - 263
  • [47] Osteoblastic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells on P3HT Thin Polymer Film
    Campione, Paola
    Rizzo, Maria Giovanna
    Bauso, Luana Vittoria
    Ielo, Ileana
    Messina, Grazia Maria Lucia
    Calabrese, Giovanna
    JOURNAL OF FUNCTIONAL BIOMATERIALS, 2025, 16 (01)
  • [48] Human Serum is a Suitable Supplement for the Osteogenic Differentiation of Human Adipose-Derived Stem Cells Seeded on Poly-3-Hydroxibutyrate-Co-3-Hydroxyvalerate Scaffolds
    Chagas de Paula, Ana Claudia
    Cavalcanti Zonari, Alessandra Arcoverde
    da Mata Martins, Thais Maria
    Novikoff, Silviene
    Pereira da Silva, Alexandra Rodrigues
    Correlo, Vitor Manuel
    Reis, Rui L.
    Gomes, Dawidson Assis
    Goes, Alfredo Miranda
    TISSUE ENGINEERING PART A, 2013, 19 (1-2) : 277 - 289
  • [49] Exosomes from human adipose-derived mesenchymal stem cells attenuate localized scleroderma fibrosis by the let-7a-5p/TGF-βR1/Smad axis
    Wang, Liquan
    Li, Tianhao
    Ma, Xuda
    Li, Yunzhu
    Li, Zhujun
    Li, Ziming
    Yu, Nanze
    Huang, Jiuzuo
    Han, Qin
    Long, Xiao
    JOURNAL OF DERMATOLOGICAL SCIENCE, 2023, 112 (01) : 31 - 38
  • [50] Downregulation of DNA methyltransferase-3a ameliorates the osteogenic differentiation ability of adipose-derived stem cells in diabetic osteoporosis via Wnt/β-catenin signaling pathway
    Zhang, Maorui
    Gao, Yujin
    Li, Qing
    Cao, Huayue
    Yang, Jianghua
    Cai, Xiaoxiao
    Xiao, Jingang
    STEM CELL RESEARCH & THERAPY, 2022, 13 (01)
12345