Pharmacokinetics and safety of olaparib tablets as monotherapy and in combination with paclitaxel: results of a Phase I study in Chinese patients with advanced solid tumours

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作者
Peng Yuan
Jianzhong Shentu
Jianming Xu
Wendy Burke
Kate Hsu
Maria Learoyd
Min Zhu
Binghe Xu
机构
[1] Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC),National Clinical Research Center for Cancer/Cancer Hospital, National Cancer Center
[2] The First Affiliated Hospital of Zhejiang University,Research Center for Clinical Pharmacy, State Key Laboratory for Diagnosis and Treatment of Infectious Disease
[3] Academy of Military Medical Sciences,Affiliated Hospital Cancer Center, The 307th Hospital of Chinese People’s Liberation Army
[4] Covance Clinical Research Unit,undefined
[5] AstraZeneca,undefined
[6] AstraZeneca,undefined
来源
关键词
Chinese patients; Olaparib; Paclitaxel; PARP inhibitor; Pharmacokinetics; Safety;
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中图分类号
学科分类号
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页码:963 / 974
页数:11
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