Pancreatic β-cell mRNA modification as a marker for type 2 diabetes

被引：0
|
作者：
Erik Renström
Enming Zhang
机构：
[1] Lund University,Lund University Diabetes Centre, Exodiab Strategic Research Area in Diabetes, Department of Clinical Sciences Malmö
来源：
Nature Metabolism | 2019年 / 1卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Diabetes mellitus invariably involves impaired regulation of insulin secretion from pancreatic β cells, as a result of unfavourable environmental influences in combination with aberrant expression of risk genes at either the transcriptional or the translational level. A recent report in Nature Metabolism explores a novel role of mRNA methylation in β-cell function and suggests that its downregulation causes type 2 diabetes.
引用
收藏
页码：748 / 749
页数：1
相关论文
共 50 条
  • [31] Epigenetic aspects of pancreatic beta cell function in type 2 diabetes
    Miriam Cnop
    Archives of Public Health, 72 (Suppl 1)
  • [32] Beta cell connectivity in pancreatic islets: a type 2 diabetes target?
    Rutter, Guy A.
    Hodson, David J.
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2015, 72 (03) : 453 - 467
  • [33] Quantification of pancreatic elasticity in type 2 diabetes: A new potential imaging marker for evaluation of microangiopathy
    He, Yu
    Jin, Ying
    Li, Xiaoping
    Wu, Lingyu
    Jin, Chunxiang
    EUROPEAN JOURNAL OF RADIOLOGY, 2020, 124
  • [34] The Proteomic Analysis of Pancreatic Exocrine Insufficiency Protein Marker in Type 2 Diabetes Mellitus Patients
    Srihardyastutie, Arie
    Soeatmadji, D. W.
    Fatchiyah
    Aulanni'am
    INTERNATIONAL CONFERENCE ON CHEMISTRY AND MATERIAL SCIENCE (IC2MS) 2017, 2018, 299
  • [35] Lifestyle modification in Type 2 diabetes
    Skinner, TC
    Lawrence, IG
    DIABETIC MEDICINE, 2002, 19 : 4 - 6
  • [36] Lifestyle modification for Type 2 diabetes
    Lee, H
    Kim, K
    Han, K
    Min, K
    Kim, E
    Ahn, K
    Ahn, H
    DIABETOLOGIA, 2004, 47 : A245 - A245
  • [37] Which Type 2 Diabetes Marker is better?
    不详
    DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2021, 146 (22)
  • [38] Identification of marker genes for type 2 diabetes
    A. Rasche
    R. Herwig
    Genes & Nutrition, 2007, 2 : 137 - 137
  • [39] Identification of marker genes for type 2 diabetes
    Rasche, A.
    Herwig, R.
    GENES AND NUTRITION, 2007, 2 (01): : 137 - 137
  • [40] Incretin and Pancreatic (3-Cell Function in Patients with Type 2 Diabetes
    Ahn, Chang Ho
    Oh, Tae Jung
    Min, Se Hee
    Cho, Young Min
    ENDOCRINOLOGY AND METABOLISM, 2023, 38 (01) : 1 - 9
12345