A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

被引：0

作者：

Ellen L Goode

Georgia Chenevix-Trench

Honglin Song

Susan J Ramus

Maria Notaridou

Kate Lawrenson

Martin Widschwendter

Robert A Vierkant

Melissa C Larson

Susanne K Kjaer

Michael J Birrer

Andrew Berchuck

Joellen Schildkraut

Ian Tomlinson

Lambertus A Kiemeney

Linda S Cook

Jacek Gronwald

Montserrat Garcia-Closas

Martin E Gore

Ian Campbell

Alice S Whittemore

Rebecca Sutphen

Catherine Phelan

Hoda Anton-Culver

Celeste Leigh Pearce

Diether Lambrechts

Mary Anne Rossing

Jenny Chang-Claude

Kirsten B Moysich

Marc T Goodman

Thilo Dörk

Heli Nevanlinna

Roberta B Ness

Thorunn Rafnar

Claus Hogdall

Estrid Hogdall

Brooke L Fridley

Julie M Cunningham

Weiva Sieh

Valerie McGuire

Andrew K Godwin

Daniel W Cramer

Dena Hernandez

Douglas Levine

Karen Lu

Edwin S Iversen

Rachel T Palmieri

Richard Houlston

Anne M van Altena

Katja K H Aben

机构：

[1] Mayo Clinic College of Medicine,Department of Health Sciences Research

[2] The Queensland Institute of Medical Research,Department of Oncology

[3] Post Office Royal Brisbane Hospital,Department of Gynaecological Oncology

[4] Cancer Research United Kingdom,Department of Gynecology and Obstetrics

[5] University of Cambridge,Department of Virus

[6] Strangeways Research Laboratory,Department of Medicine

[7] University College London,Department of Community and Family Medicine

[8] Elizabeth Garrett Anderson (EGA) Institute for Women's Health,Department of Epidemiology

[9] The Juliane Marie Centre,Division of Epidemiology and Biostatistics

[10] Hormones and Cancer Institute of Cancer Epidemiology,Department of Genetics and Pathology

[11] Danish Cancer Society,Division of Cancer Epidemiology and Genetics

[12] Massachusetts General Hospital,Department of Pathology

[13] Duke University Medical Center,Division of Epidemiology and Biostatistics, Department of Health Research and Policy

[14] Centre for Molecular Oncology and Imaging,Department of Epidemiology

[15] Institute of Cancer,Department of Preventive Medicine

[16] Barts and The London School of Medicine and Dentistry,Division of Cancer Epidemiology

[17] Biostatistics and Health Technology Assessment (HTA),Department of Cancer Genetics

[18] Radboud University Nijmegen Medical Centre,Department of Obstetrics and Gynecology

[19] University of New Mexico,Department of Gynecology and Obstetrics

[20] Alberta Health Services-Cancer Care,Department of Virus

[21] International Hereditary Cancer Center,Department of Laboratory Medicine and Pathology

[22] Pomeranian Medical University,Department of Medical Oncology

[23] National Cancer Institute,Department of Statistics

[24] National Institutes of Health,Department of Epidemiology

[25] The Royal Marsden Hospital,Department of Gynaecology

[26] Gynecological Oncology Unit,Department of Biomedical Physiology and Kinesiology

[27] Centre for Cancer Genomics and Predictive Medicine,Department of Public Health and Primary Care

[28] Peter MacCallum Cancer Centre,Department of Epidemiology and Public Health

[29] University of Melbourne,Department of Obstetrics and Gynecology

[30] Stanford University School of Medicine,Department of Gynecology and Obstetrics

[31] University of South Florida,Department of Cancer Epidemiology and Prevention

[32] Pediatrics Epidemiology Center,Division of Hematology and Oncology, Department of Medicine

[33] College of Medicine,Department of Gynaecologic Oncology

[34] H. Lee Moffitt Cancer Center and Research Institute,Department of Obstetrics and Gynecology

[35] School of Medicine,Department of Obstetrics and Gynecology

[36] University of California,Department of Pathology

[37] University of Southern California,Cancer Research United Kingdom Department of Oncology

[38] Keck School of Medicine,Department of Public Health and Primary Care

[39] Vesalius Research Center,undefined

[40] Flanders interuniversity Institute of Biotechnology (VIB) and K.U,undefined

[41] Program in Epidemiology,undefined

[42] Fred Hutchinson Cancer Research Center,undefined

[43] Seattle,undefined

[44] German Cancer Research Center (DKFZ),undefined

[45] Roswell Park Cancer Institute,undefined

[46] University of Hawaii,undefined

[47] Cancer Research Center,undefined

[48] Clinics of Obstetrics and Gynaecology,undefined

[49] Hannover Medical School,undefined

[50] Helsinki University Central Hospital,undefined

来源：

Nature Genetics | 2010年 / 42卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

Simon Gayther and colleagues report a genome wide association study for ovarian cancer. They identify two new susceptibility loci at 2q31 and 8q24 and two suggestive susceptibility loci at 3q25 and 17q21.

引用

页码：874 / 879

页数：5

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